F. Guo

This study reports the largest sequenced plant genome, Paris polyphylla var. yunnanensis, and identifies genes involved in polyphyllin biosynthesis.

This paper introduces an acoustofluidic device to create 3D neurospheroids for modeling Alzheimer's disease neuroinflammation and amyloid-β toxicity.

This paper develops a microfluidic platform to assemble human brain organoids and models prenatal cannabis exposure effects on early brain development.

This study identifies 5 small molecules that inhibit amyloid-β aggregation at the cell-membrane interface, which is relevant for Alzheimer's disease.

The paper assesses the frequency of deleterious mutations in 21 hereditary breast and ovarian cancer genes among 882 high-risk Chinese individuals, finding 19.5% carried such mutations, with higher rates in those with both breast and ovarian cancer histories.

This study models the transmembrane potential distribution of cells under nanosecond pulsed electric fields by incorporating dielectric relaxation and electroporation effects.

The paper identifies a novel double-membraned vesiculation process in planarian oocytes during nuclear envelope breakdown, revealing evolutionary adaptability of NEBD.