Author

G. Nie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

C. Xu· 1 shared D. Drew· 1 shared F. J. Rossello· 1 shared G. Liu· 1 shared G. Sun· 1 shared H. Singh· 1 shared J. A. Neil· 1 shared J. Chen· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBioengineering

C. Xu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Rationally designed multimeric nanovaccines using icosahedral DNA origami for molecularly controlled display of SARS-CoV-2 receptor binding domain

Q. Feng, K. Cheng, L. Zhang, X. Gao, J. Liang, G. Liu, N. Ma, C. Xu, M. Tang, L. Chen, X. Wang, X. Ma, J. Zou, Q. Shi, P. Du, , X. Zhao

This study designs multimeric nanovaccines using icosahedral DNA origami to display SARS-CoV-2 RBD, showing enhanced B cell activation and immune responses in mice.

bioRxiv · Aug 24, 2023 · PreprintBioengineering

An iTSC-derived placental model of SARS-CoV-2 infection unveils ACE2-dependent susceptibility in syncytiotrophoblasts

J. Chen, J. A. Neil, J. P. Tan, R. Rudraraju, M. Mohenska, Y. B. Sun, G. Sun, Y. Zhou, Y. Li, D. Drew, P. Pymm, W.-H. Tham, F. J. Rossello, G. Nie, X. Liu, , J. M. Polo

This study develops an in vitro model of SARS-CoV-2 infection in placental cells using iTSCs, showing that syncytiotrophoblasts are infected and that ACE2 inhibition prevents infection and restores function.

bioRxiv · Oct 27, 2021 · PreprintCell Biology

HtrA1 alters endothelial tube formation characteristics in an in vitro model

H. Singh, G. Nie

This study shows that high HtrA1 levels alter endothelial tube formation in an in vitro model, leading to more but shorter and broken tubes, suggesting a role in AMD and PE.

bioRxiv · Feb 3, 2019 · PreprintCell Biology