Author

H. Gan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. Fang· 1 shared C. He· 1 shared C. R. Secreto· 1 shared C. Yu· 1 shared D. Fang· 1 shared D. J. Daniels· 1 shared E. Braggio· 1 shared F. Lan· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

C. Fang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TERT accelerates BRAF mutant-induced thyroid cancer dedifferentiation and progression by regulating ribosome biogenesis

P. Yu, N. Qu, R. Zhu, J. Hu, P. Han, L. Tan, H. Gan, C. He, C. Fang, Y. Lei, J. Li, C. He, F. Lan, X. Shi, W. Wei, , Y.-l. Wang

This study shows TERT promotes thyroid cancer dedifferentiation and progression by enhancing ribosome biogenesis, and inhibiting rRNA synthesis can reverse this process.

bioRxiv · Jan 29, 2023Cancer Biology

B Cell Receptor Signaling Drives APOBEC3 Expression Via Direct Enhancer Regulation in Chronic Lymphocytic Leukemia B Cells

Z. Wang, H. Yan, J. C. Boysen, C. R. Secreto, J. Zhong, J. Zhou, H. Gan, C. Yu, E. Braggio, S. L. Slager, S. A. Parikh, N. E. Kay

This study shows BTKi treatment reduces APOBEC3 expression in CLL B cells through enhancer regulation, linking BCR signaling to genomic instability.

bioRxiv · Jul 27, 2021Cancer Biology

Single cell transcriptome analysis of decidua macrophages in normal and recurrent spontaneous abortion patients

Q. Zheng, X. Xu, F. Yang, H. Gan, Y. Zhao, X. Wan, L. Jin

The paper profiles single-cell transcriptomes of decidual macrophages in normal and recurrent spontaneous abortion patients, identifying distinct polarization states and potential therapeutic targets.

bioRxiv · Mar 23, 2021 · PreprintCell Biology

H3K27me3-mediated silencing of Wilms Tumor 1 supports the proliferation of brain tumor cells harboring the H3.3K27M mutation

D. Fang, H. Gan, L. Cheng, J.-H. Lee, H. Zhou, J. N. Sarkaria, D. J. Daniels, Z. Zhang

This study shows that H3K27me3 silencing of WT1 supports DIPG cell proliferation, despite global H3K27me3 loss due to H3.3K27M mutation.

bioRxiv · Mar 6, 2017Cancer Biology