L. Kelly

HMGB1/CXCL12 heterocomplex activates CXCR4 to suppress the ability of Muller glia to become proliferating progenitor-like cells in the chick retina

This study shows HMGB1/CXCL12 heterocomplex activates CXCR4 to suppress Muller glia reprogramming into progenitor-like cells in chick retinas after injury.

Genetic barcodes for ash (Fraxinus) species and generation of new wide hybrids

This paper develops a genetic barcode system for ash species and generates wide hybrids to transfer resistance traits against pests and pathogens.

The influence of talus size and shape on in vivo talocrural hopping kinematics

This study examines how talus shape affects hopping kinematics in healthy individuals, finding that shape influences talar dome orientation and curvature beyond size.

Bacteriophage cocktail shows no toxicity and improves the survival of Galleria mellonella infected with Klebsiella spp.

The paper tests a bacteriophage cocktail against Klebsiella spp. in vitro and in a Galleria mellonella model, showing it is safe and improves survival.

Human in vivo midtarsal and subtalar joint kinematics during walking, running, and hopping

The paper analyzes midtarsal and subtalar joint kinematics during walking, running, and hopping, finding that their rotation axes align with the morphological subtalar axis.

Magnetogenetic cell activation using endogenous ferritin

This paper develops a magnetogenetic method using anti-ferritin nanobodies and a benchtop electromagnet to activate cells in vivo, improving glucose tolerance in mice.

Preneoplastic cells switch to Warburg metabolism from their inception exposing multiple vulnerabilities for targeted elimination

This study shows that preneoplastic cells exhibit Warburg metabolism early on, which can be targeted to eliminate them using metabolic inhibitors.

Therapeutic modulation of the blood-brain barrier and ischemic stroke by a bioengineered FZD4-selective WNT surrogate

This study develops a bioengineered FZD4-selective WNT surrogate that improves BBB function and reduces ischemic stroke damage in mice.

Rapid polygenic adaptation in a wild population of ash trees under a novel fungal epidemic

The paper shows rapid polygenic adaptation in ash trees due to a fungal epidemic, with a 31% juvenile population decline estimated through simulations.

Resolving the structure of phage-bacteria interactions in the context of natural diversity

The paper studies phage-bacteria interactions in marine environments, finding sparse killing and common recombination among phages.

Bacterial Swarmers exhibit a Protective Response to Intestinal Stress

This study identifies bacterial swarmers as protective against intestinal inflammation in mice and humans, showing their ability to enrich beneficial gut microbes.

Resolving phylogeny and polyploid parentage using genus-wide genome-wide sequence data from birch trees

This study resolves the phylogeny and polyploid parentage of birch trees using genome-wide sequence data, revealing two subgenera and complex reticulate origins of polyploid taxa.

Isolation and chacterisation of Klebsiella phages for phage therapy

This study isolates and characterizes 30 novel Klebsiella phages, finding that lytic phages are most suitable for therapy but single phages are insufficient due to rapid resistance development.

MicroRNA composition delineates cardiosphere-derived cell and mesenchymal stem cell extracellular vesicles

The paper compares extracellular vesicles from cardiosphere-derived cells and mesenchymal stem cells, finding differences in miR composition that distinguish their origins.