Author

N. Hou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. Zhan· 1 shared C. Peng· 1 shared C. Schindewolf· 1 shared C. Wang· 1 shared C. Zhang· 1 shared G. Chi· 1 shared G. Zhong· 1 shared H. Gao· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperMicrobiology

B. Zhan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Development of highly potent non-covalent inhibitors of SARS-CoV-2 3CLpro

N. Hou, L. Shuai, L. Zhang, X. Xie, K. Tang, Y. Zhu, Y. Yu, W. Zhang, Q. Tan, G. Zhong, Z. Wen, C. Wang, X. He, H. Huo, H. Gao, , Q. Hu

This study develops a potent non-covalent inhibitor of SARS-CoV-2 3CLpro, showing effective antiviral activity in human cells and animal models.

bioRxiv · Aug 10, 2022 · PreprintMicrobiology

Alnustone inhibits Streptococcus pneumoniae virulence by targeting pneumolysin and sortase A

C. Zhang, T. Fang, X. Wang, L. Shi, B. Zhan, N. Hou, S. Liu, M. Bao, G. Chi

This study identifies alnustone as a drug that inhibits Streptococcus pneumoniae virulence by targeting pneumolysin and sortase A, reducing biofilm formation and protecting against infection.

bioRxiv · Mar 7, 2022Microbiology

OxyR senses reactive sulfane sulfur and activates genes for its removal in Escherichia coli

N. Hou, Z. Yan, K. Fan, H. LI, R. Zhao, Y. Xia, H. Liu, L. Xun

The paper shows OxyR in E. coli detects reactive sulfane sulfur and activates genes for its removal via thioredoxin and glutaredoxin.

bioRxiv · Feb 25, 2019Microbiology