M. Bao

Neuroprotective Mechanism of Ribisin A on H 2 O 2 -induced PC12 cell injury model

This study investigates how Ribisin A protects PC12 cells from H2O2-induced injury by enhancing antioxidant activity, reducing inflammation, and modulating the ERK/CREB signaling pathway.

Micropillar enhanced FRET-CRISPR biosensor for nucleic acid detection

This study develops a FRET-CRISPR biosensor with micropillars for HPV 16 DNA detection, showing improved sensitivity and addressing microfluidic bubble issues.

Tocilizumab treatment leads to early resolution of lymphopenia and myeloid dysregulation in patients hospitalized with COVID-19

The Effects of CdSe/ZnS Quantum Dots on the Photosynthesis Rate of the Chlorella Vulgaris Beads

This study investigates how CdSe/ZnS quantum dots affect the photosynthesis rate of Chlorella vulgaris beads, showing concentration and time-dependent effects.

On-Demand Fully-Enclosed Superhydrophobic-Optofluidic Device Enabled by High Precision Microstereolithography

This paper introduces a fully-enclosed superhydrophobic optofluidic system with low optical loss, demonstrating its application for CRISPR-labeled quantum dot quantification.

Differential modifications of the C-terminal tails of α-tubulin isoforms and their importance for kinesin-based microtubule transport in vivo

This study identifies differential glutamylation of α-tubulin isoforms in Drosophila and shows its role in Kinesin-1-dependent processes like germline transport and axonal mitochondrial trafficking.

Alnustone inhibits Streptococcus pneumoniae virulence by targeting pneumolysin and sortase A

This study identifies alnustone as a drug that inhibits Streptococcus pneumoniae virulence by targeting pneumolysin and sortase A, reducing biofilm formation and protecting against infection.

Histone H3K4 methyltransferase DcATX1 promotes ethylene induced petal senescence in carnation

This study identifies DcATX1 as a histone methyltransferase that accelerates ethylene-induced petal senescence in carnation by regulating H3K4me3 levels and gene expression.

Energy Expenditure during Cell Spreading Regulates the Stem Cells Responses to Matrix Stiffness

This study shows that energy expenditure during cell spreading on stiff substrates affects stem cell responses to matrix stiffness via AMPK activation.

High contrast probe cleavage detection on porous silicon biosensors via quantum dot labeled DNA probes

The paper demonstrates a high-contrast probe cleavage detection method using porous silicon biosensors and quantum dot-labeled DNA probes, achieving a significant signal shift for nucleic acid cleavage detection.

Quantifying synergy in the bioassay-guided fractionation of natural product extracts

The paper introduces EFICI, a method to quantify drug interactions during bioassay-guided fractionation of natural extracts, and applies it to two plant extracts against Acinetobacter baumannii.

Magnetic Bead-Quantum Dot (MB-Qdot) CRISPR Assay for Instrument-Free Viral DNA Detection

The paper develops an instrument-free CRISPR-based assay using magnetic beads and quantum dots to detect viral DNA with a detection limit of ~0.5 nM, demonstrated using African swine fever virus.

Integrated Micropillar Polydimethylsiloxane Accurate CRISPR Detection (IMPACT) System for Rapid Viral DNA Sensing

The paper develops an IMPACT system for rapid viral DNA detection using CRISPR, achieving sensitivity from 0.1 to 10 nM without fluorescent quenchers.

Single Chlamydomonas reinhardi (C. reinhardtii) cell separation from bacterial cells and auto-fluorescence tracking with a nano-sieve device

This paper develops a nano-sieve device for separating microalgae from bacteria and tracking single cells via auto-fluorescence.

High-throughput and all-solution phase African Swine Fever Virus (ASFV) detection using CRISPR-Cas12a and fluorescence based point-of-care system

This paper develops a CRISPR-Cas12a-based system for rapid, sensitive, and specific ASFV detection without nucleic acid amplification, achieving a detection limit of 100 fM.