Author

N. Traugh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1

Frequent Co-Authors

B. Wang· 2 shared M. Brown· 2 shared P. Jiang· 2 shared T. Xiao· 2 shared X. Wang· 2 shared A. Sahu· 1 shared B. Zhang· 1 shared C. A. Meyer· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

B. Wang

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Selective inhibition of fibroblast-specific Domain Discoidin Receptor 1 (DDR1) reduces collagen deposition and modulates fibroblast-specific cytokine release within the breast microenvironment.

D. E. C. Fein, N. Traugh, G. Rauner, Y. Mal, C. Trepicchio, C. Kuperwasser

This study shows that inhibiting DDR1 in breast fibroblasts reduces collagen deposition and alters cytokine release, suggesting DDR1 as a therapeutic target for fibroblast-related breast disorders.

bioRxiv · Aug 11, 2023 · PreprintCell Biology

In Vivo CRISPR Screens Identify E3 Ligase Cop1 as a Modulator of Macrophage Infiltration and Cancer Immunotherapy Target

X. Wang, C. Tokheim, B. Wang, S. S. Gu, Q. Tang, Y. Li, N. Traugh, Y. Zhang, Z. W. Li, B. Zhang, J. Fu, T. Xiao, W. Li, C. A. Meyer, J. Chu, , X. S. Liu

The paper identifies Cop1 as a modulator of macrophage infiltration and cancer immunotherapy in TNBC by using in vivo CRISPR screens and multi-omics analyses.

bioRxiv · Dec 9, 2020Cancer Biology

Genome-wide CRISPR screens identify essential cell growth mediators in BRAF-inhibitor resistant melanoma

Z. Li, B. Wang, S. Gu, P. Jiang, A. Sahu, C.-H. Chen, T. Han, S. Shi, X. Wang, N. Traugh, H. Liu, Y. Liu, Q. Wu, M. Brown, T. Xiao, , S. Liu

The paper identifies key regulators of BRAF inhibitor resistance in melanoma using CRISPR screens and integrates multi-omics data to reveal CDK6-dependent mechanisms.

bioRxiv · Dec 16, 2019Cancer Biology