clustering

Sensory and Motor Building Blocks of an Extra Robotic Digit Representation

The paper examines how the brain represents a robotic extra digit and shows that its representation in M1 becomes more distinct and sensory-dominated with prolonged use.

Pupil size reflects effort but not motor fatigability during a sustained motor task

This study investigates whether pupil size reflects physical effort or motor fatigability during sustained repetitive movement and finds that it reflects effort but not fatigability.

Dual CD40/CD28 co-stimulation reprograms the solid-tumor microenvironment to unleash CAR-T and endogenous anti-tumor immunity

This paper introduces LACO-Stim, a co-stimulatory molecule that enhances CAR-T cell therapy by reprogramming the tumor microenvironment to support endogenous anti-tumor immunity.

Decoupled Surface Engineering Enables Cell-Interactive Edible Microcarriers across Food-Grade Polysaccharides

This paper develops a surface-engineering strategy for edible microcarriers that enhances cell adhesion without limiting material choice, showing improved cell attachment on multiple polysaccharides and cell types.

Replication-stress response shapes Leishmania genome plasticity through non-equivalent RAD9 and HUS1 functions.

This study shows that HUS1 and RAD9 subunits of the 9-1-1 checkpoint clamp have opposing roles in shaping genome plasticity in Leishmania major through distinct replication-stress responses and genome remodelling patterns.

Telotrons: spliceosomal introns composed of telomeric repeats

The paper identifies telotrons, telomeric repeat-containing introns, in multiple eukaryotic genomes and suggests telomerase drives intron creation and remodeling.

A shared wireless acquisition core for cortical and peripheral recordings in freely moving mice

This paper introduces a wireless headstage for simultaneous cortical, muscle, and movement recordings in freely moving mice, demonstrating its utility in seizure detection and behavior-related neural activity analysis.

Automatic orofacial behaviors remap within cortical substrates for voluntary motor control in freely moving primates

This study identifies cortical substrates involved in modulating automatic orofacial behaviors in macaques, showing distinct neural dynamics for voluntary and automatic actions.

Integrating Microbial Ecology and Sustainability: Linking Agricultural Waste Gas Streams to Microbial Community Shifts in a Photobioreactor

This study examines microbial community dynamics in a photobioreactor using agricultural waste gas streams, showing spatially structured communities and partial nitrogen recovery.

Tissue-like Viscoelasticity Drives Muscle Stem Cell Expansion Through Mechanical Memory Formation

This study shows that tissue-like viscoelastic substrates enhance muscle stem cell expansion by creating mechanical memory through focal adhesion stabilization and Rac-Akt signaling.

Early visual cortex is not functionally necessary for temporal attention: A TMS study

Impact of iron-enriched diets on the nutritional composition and microbiome diversity of house crickets (Acheta domesticus)

This study investigates how varying iron levels in diets affect the nutritional profile and microbiome of house crickets, finding that high iron increases their iron content without altering microbial diversity.

Assembly of host-specific bacterial and fungal communities from soil by diverse subaerial green algae

This study shows subaerial green algae from Chlorophyta and Streptophyta assemble distinct phycosphere communities from soil, with host identity driving bacterial composition more strongly than fungal.

Identification and characterization of new P. aeruginosa phages using a surface receptor platform

The paper introduces a SURFAR platform to identify and characterize new P. aeruginosa phages by targeting specific receptors, isolating two novel phages with distinct host ranges.

From Fill to Freeze: Redesigning homeRNA to Enable Robust Sampling and Scalable Downstream Processing Workflows for Remote Blood Transcriptomics

This paper validates the redesigned homeRNA platform's robustness to remote study stresses, showing it maintains RNA quality under varied conditions and storage times.

Breaking the bottleneck: semi-automated quantification of actin filament dynamics

The paper introduces SMAUG, a semi-automated tool for analyzing actin filament dynamics from TIRF microscopy images, reducing analysis time while maintaining accuracy.

Sex differences in agonistic social behavior: Effects of exercise and ovariectomy

This study examines how sex, exercise, and ovariectomy affect offensive and defensive aggression in rats, finding sex-specific behavioral differences and no effect of exercise.

SNAzzy: an image processing pipeline for investigating global Synchronous Network Activity

SNAzzy processes and analyzes high-throughput microscopy data from Drosophila embryos to study synchronous network activity.

Integrative identification of Tetratostichococcus sp. CCAH0201 (Trebouxiophyceae, Chlorophyta) from Rhizophora leaves in the Can Gio Mangrove Forest, Vietnam

The paper identifies a microalgal strain from mangrove leaves using molecular markers and phylogenetic analysis, placing it closely related to Tetratostichococcus jenerensis.

Extended Pavlovian conditioned approach training and devaluation in Long-Evans rats using time-restricted feeding

This study develops an extended Pavlovian conditioned approach paradigm in Long-Evans rats under time-restricted feeding to better identify phenotypes linked to compulsive behaviors and stress-related dysregulation.

The C. elegans Connectome Toolbox: an open, extensible framework for multimodal connectomic data integration and analysis

The paper introduces the C. elegans Connectome Toolbox, a framework for integrating and analyzing multimodal connectomic data, enabling comparison across datasets and modalities.

Capturing and Characterising Wild Yeast for Beer Brewing

The paper develops a pipeline to collect, characterize, and scale wild yeast for beer brewing, identifying interventions to overcome industrial fermentation challenges.

Live attenuated YFV-17D vaccine induces robust B and T cell immunity in vaccine-draining lymph nodes

This study examines immune dynamics in lymph nodes after YFV-17D vaccination, identifying robust B and T cell responses and a conserved germinal center program across different vaccines.

Clonally Convergent Tph/Tfh-like CD4+ T Cells are Shared Across Recovery and Recurrence in Experimental Periodontitis

The paper identifies clonally convergent Tfh/Tph-like CD4+ T cells that persist in the mucosa after recovery from periodontitis and contribute to recurrence.

A microstructural analysis of water intake patterns associated with light phase food and water restriction in male and female rats.

The paper examines how food and water intake patterns in rats change under light phase restrictions, finding that food access timing more strongly influences water intake than water access timing influences food intake.

Single-Cell RNA Sequencing Reveals Distinct Cellular and Molecular Features of Steroid-Induced Osteonecrosis of the Femoral Head Compared to Alcohol-Induced Osteonecrosis and Hip Osteoarthritis

This study uses single-cell RNA sequencing to compare cellular and molecular features of steroid-induced and alcohol-induced osteonecrosis of the femoral head with hip osteoarthritis, identifying distinct immune and stromal cell signatures.

A large, distinct family of RNase H fold nucleases associated with numerous defense systems in prokaryotes

The paper identifies and characterizes a new family of prokaryotic defense proteins, WARDs, which are associated with various defense systems and provide phage resistance.

High-fat diet promotes exhaustion-associated T-cell remodeling across vascular and lymphoid tissues in atherosclerosis-prone mice

This study shows that a high-fat diet causes T-cell exhaustion in multiple tissues of atherosclerosis-prone mice, which partially reverses with dietary changes.

CD200R1 Marks a Branchpoint During Human Natural Killer Cell Development in Tonsils

The paper identifies CD200R1 as a marker for an immature NK-cell precursor in tonsils, distinguishing between oligopotent and more restricted developmental stages.

The intrinsically disordered N-terminal region of eIF5B nucleates RNA-driven phase separation

This study shows that the intrinsically disordered N-terminal region of eIF5B drives RNA-driven phase separation in vitro and validates this in cells.