C. Huang

This study develops a reversed paired-gRNA plasmid cloning strategy to eliminate plasmid instability caused by direct repeats, achieving efficient genome editing in E. coli.

This study investigates the role of prolactin receptor signaling in beta-cell function during pregnancy, finding both cell-autonomous and non-cell-autonomous effects on glucose regulation and gene expression.

This study develops microscaled proteogenomic methods for cancer analysis, showing treatment response and resistance mechanisms in ERBB2-positive breast cancers.

The paper tests metagenomic sequencing with ONT MinION for strain-level identification of bacterial tomato pathogens, achieving success with Pto but showing challenges with field samples.

This paper demonstrates that CRISPR-Cas9-assisted native end-joining editing can efficiently knock out large genomic regions in E. coli without exogenous repair systems.

This paper develops a method to measure cell membrane micromechanics using fluorescence lifetime imaging of DiI, enabling analysis of lipid bilayer properties in situ.

This study shows that age-dependent protein aggregation in C. elegans forms amyloid-like structures and accelerates tissue functional decline, suggesting a role for protein aggregation in aging.

This study examines the sterilization effects of cavitation-shock interactions on marine Vibrio sp. through experimental and modeling approaches.

This study analyzes TCRB and IGH repertoires in IgAN patients to identify non-invasive biomarkers for diagnosis.