T. Ding

Super homotypic targeting by exosome surface engineering

This paper enhances homotypic targeting by engineering exosome surfaces with lanthanides, significantly improving cell-exosome interactions and enabling new applications in diagnostics and therapy.

Flow zoometry of Drosophila

This paper introduces flow zoometry, a high-throughput screening method for Drosophila, enabling rapid, automated, and high-resolution analysis of whole animals.

Single-Molecule Orientation Imaging Reveals the Nano-Architecture of Amyloid Fibrils Undergoing Growth and Decay

This study uses SMOLM to analyze A{beta}42 fibril architecture and dynamics, finding that order and heterogeneity correlate with growth and decay.

Resolving the nanoscale structure of β-sheet assemblies using single-molecule orientation-localization microscopy

This study uses single-molecule orientation-localization microscopy to analyze the structure and polymorphism of engineered and pathological cross-beta fibrils.

A Self-Healing, Viscoelastic Hydrogel Promotes Healing of Brain Lesions

This paper develops a self-healing hydrogel that mimics brain parenchyma viscoelasticity to promote healing of brain lesions in mice.

Enteroendocrine cell types that drive food reward and aversion

The paper identifies enteroendocrine cell subtypes that influence food reward and aversion through distinct signaling pathways in mice.

Single-Molecule Localization Microscopy of 3D Orientation and Anisotropic Wobble using a Polarized Vortex Point Spread Function

This paper introduces a polarized vortex PSF to simultaneously measure 3D orientation and anisotropic wobble of single molecules from a single image, achieving high precision in localization, orientation, and wobble.

Quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy

This paper introduces a method to measure the accuracy of single-molecule localization microscopes directly on experimental data without ground-truth knowledge.

Single-molecule 3D orientation imaging reveals nanoscale compositional heterogeneity in lipid membranes

The paper introduces SMOLM, a single-molecule orientation localization microscopy technique, to measure orientation and spatial organization of lipophilic probes in lipid membranes, revealing compositional heterogeneity.

Single-molecule orientation localization microscopy for resolving structural heterogeneities between amyloid fibrils

The paper introduces a new performance metric, VUB, to efficiently evaluate orientation measurement performance of PSFs and applies it to study structural heterogeneities in amyloid fibrils using single-molecule orientation localization microscopy.

Reversed paired-gRNA plasmid cloning strategy for efficient genome editing in Escherichia coli

This study develops a reversed paired-gRNA plasmid cloning strategy to eliminate plasmid instability caused by direct repeats, achieving efficient genome editing in E. coli.

Microbial composition of the human nasopharynx varies according to influenza virus type and vaccination status.

The paper examines how influenza virus type and vaccination status influence nasopharyngeal microbiota composition in infected individuals and healthy controls.

CRISPR-Cas9-assisted native end-joining editing offers a simple strategy for efficient genetic engineering in Escherichia coli

This paper demonstrates that CRISPR-Cas9-assisted native end-joining editing can efficiently knock out large genomic regions in E. coli without exogenous repair systems.