C. Morris

Computational Discovery of an Allosteric Pocket on APOBEC3B and the Impact of Metal Contamination on Inhibitor Validation

This study identifies a novel allosteric pocket on APOBEC3B using computational methods but finds that metal contamination in screening samples led to false positive inhibitor results.

The WD Domain Of Atg16l1 Crucial For LC3-Associated Phagocytosis Is Not Required For Preserving Skin Homeostasis In Mice

This study investigates the role of Atg16l1 in skin homeostasis using LAP-deficient mice, finding no significant cutaneous phenotype despite histological differences.

A paper based microfluidic platform combining LAMP-CRISPR/Cas12a for fluorometric detection of nucleic acids

This paper demonstrates a paper-based microfluidic platform combining LAMP and CRISPR/Cas12a for specific nucleic acid detection, reducing false positives and improving robustness and cost-effectiveness compared to conventional methods.

Associative nitrogen fixation could be common in South African mesic grassland

The paper investigates nitrogen fixation in South African grasslands by detecting nifH gene presence in root samples, finding it ubiquitous across species and increased after fire.

Will The Grass Be Greener On The Other Side Of Climate Change?

The paper assesses how climate change may affect forage quality in different South African grasslands, predicting declines in sourveld but stability in sweetveld.

Antimicrobial resistance in dairy slurry tanks: a critical point for measurement and control

This study identifies dairy slurry tanks as critical for antimicrobial resistance (AMR) prevalence and control, showing that 60 days of storage can reduce ARB spread by >99%.

Vascular proteome responses precede organ dysfunction in sepsis

This study identifies vascular proteome changes preceding organ dysfunction in sepsis using a murine model and integrative analysis.

#COVIDisAirborne: AI-Enabled Multiscale Computational Microscopy of Delta SARS-CoV-2 in a Respiratory Aerosol

This paper uses AI-enabled multiscale computational microscopy to study SARS-CoV-2 Delta variant in respiratory aerosols, revealing atomic-level insights into airborne transmission.

Buried but unsafe - defoliation depletes the underground storage organ (USO) of the mesic grassland geophyte, Hypoxis hemerocallidea

This study shows that repeated defoliation reduces underground storage organs in Hypoxis hemerocallidea, impairing regrowth and threatening forb survival in overgrazed grasslands.

Is a long hygroscopic awn an advantage for Themeda triandra in drier areas?

The study tests if longer hygroscopic awns in Themeda triandra help seeds move further in drier areas, finding longer awns move faster but not necessarily longer.

A clinically and genomically annotated nerve sheath tumor biospecimen repository.

The paper establishes a clinically and genomically annotated nerve sheath tumor biospecimen repository to support research on NF1-related tumors.

Experimental evolution reveals a novel avenue to release catabolite repression via mutations in XylR

This study evolves E. coli strains with mutations in XylR to enhance xylose fermentation without glucose repression, achieving high efficiency in mixed sugar utilization.