Author

F. Rodriguez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 2 Immunology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Organism:mouse· 3 Assay:whole-genome sequencing· 3 Assay:bulk RNA-seq· 2

Frequent Co-Authors

A. Babaian· 1 shared A. Belzberg· 1 shared A. Bernand· 1 shared A. Camejo· 1 shared A. Dykema· 1 shared A. Gaigneaux· 1 shared A. Hiller· 1 shared A. Jainarayanan· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 5 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Babaian

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Perforin-mediated pore formation at the lytic synapse triggers the canonical pyroptotic cell death pathway

B. McKenzie, M.-P. Puissegur, L. Demeersseman, F. Rodriguez, E. Cini, A. Jainarayanan, M. A. Widdess, C. C. Staton, L. Chen, V. Sibaud, L. Lamant, M. L. Dustin, A. Bernand, S. Mueller, S. Valitutti

This study shows perforin triggers pyroptosis in target cells by activating the NLRP3/caspase-1/gasdermin D pathway, while sustained CTL interaction leads to apoptosis.

bioRxiv · May 24, 2024 · PreprintCell Biology

The gut microbiome-linked long chain fatty acid stearate suppresses colorectal cancer

M. Tsenkova, M. Brauer, V. Pozdeev, M. Kasakin, S. B. Busi, M. Schmoetten, D. Cheung, M. Meyers, F. Rodriguez, A. Gaigneaux, E. Koncina, C. Gilson, L. Schlicker, D. Herebian, M. Schmitz, , E. Letellier

This study shows that the ketogenic diet reduces colorectal tumors in mice by altering the gut microbiome to increase stearic acid, which suppresses cancer cell growth and immune responses.

bioRxiv · Dec 7, 2023 · PreprintCancer Biology

A Parasite Odyssey: An RNA virus concealed in Toxoplasma gondii

P. Gupta, A. Hiller, J. Chowdhury, D. Lim, D. Y. Lim, J. P. Saeij, A. Babaian, F. Rodriguez, L. Pereira, A. Morales

The paper identifies a novel narnavirus, Apocryptovirus odysseus, potentially infecting Toxoplasma gondii, and suggests it may act as a pro-inflammatory factor in host cells.

bioRxiv · Sep 17, 2023 · PreprintMicrobiology

Distinct Myeloid Derived Suppressor Cell Populations Promote Tumor Aggression in Glioblastoma

C. Jackson, C. Cherry, S. Bom, A. Dykema, E. Thompson, M. Zheng, Z. Ji, W. Hou, R. Li, H. Zhang, J. Choi, F. Rodriguez, J. Weingart, S. Yegnasubramanian, M. Lim, , D. Pardoll

This study identifies two unique myeloid-derived suppressor cell populations in glioblastoma that promote tumor growth and immune evasion.

bioRxiv · Mar 26, 2023 · PreprintImmunology

Evolutionary dynamics of transposable elements in bdelloid rotifers

R. W. Nowell, C. G. Wilson, P. Almeida, P. H. Schiffer, D. Fontaneto, L. Becks, F. Rodriguez, I. R. Arkhipova, T. G. Barraclough

This study analyzes TE dynamics in bdelloid rotifers, finding active TEs at frequencies similar to sexual species and expanded RNAi-related genes.

bioRxiv · Sep 15, 2020Evolutionary Biology

The genetic variation landscape of African swine fever virus reveals frequent positive selection and adaptive flexibility

Y.-J. Bao, J. Qiu, Y. Luo, F. Rodriguez, H.-J. Qiu

This study analyzes genetic variation in African swine fever virus to identify positive selection and adaptive flexibility linked to host interactions.

bioRxiv · Aug 12, 2020Evolutionary Biology

Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5

A. K. Kongsomboonvech, F. Rodriguez, A. L. Diep, B. M. Justice, B. E. Castallanos, A. Camejo, D. Mukhopadhyay, G. A. Taylor, M. Yamamoto, J. P. J. Saeij, M. L. Reese, K. Jensen

This study identifies NLRP3-dependent but inflammasome-independent pathways regulating CD8 T cell IFNγ responses to Toxoplasma gondii vacuolar antigens, independent of ROP5 virulence factors.

bioRxiv · Jan 20, 2020Immunology

A clinically and genomically annotated nerve sheath tumor biospecimen repository.

K. Pollard, J. Banerjee, X. Doan, J. Wang, X. Guo, R. J. Allaway, S. Langmead, B. Slobogean, C. Meyer, D. Loeb, C. Morris, A. Belzberg, J. O. Blakeley, F. Rodriguez, J. Guinney, , C. A. Pratilas

The paper establishes a clinically and genomically annotated nerve sheath tumor biospecimen repository to support research on NF1-related tumors.

bioRxiv · Dec 19, 2019Cancer Biology