C. Yan

The paper presents a high-resolution cryo-EM structure of the Xenopus laevis nuclear pore complex cytoplasmic ring, revealing new structural features and interactions.

This study identifies miR-574 as a regulator of FAM210A, which influences mitochondrial protein expression and cardiac remodeling in heart failure.

The paper reports the cryo-EM structure of the human TIM22 complex at 3.7 angstrom resolution, revealing its architecture and potential mechanism for protein import.

The paper identifies CsHscB from Clonorchis sinensis as a TLR2 agonist that modulates macrophage activation and IL-10 production through TLR2-dependent mechanisms.

This study identifies the Sam50-Mic19-Mic60 axis as critical for mitochondrial cristae architecture by connecting SAM and MICOS complexes through OMA1-mediated cleavage of Mic19.

This study reports cryo-EM structures of two late-stage human spliceosomes, revealing insights into exon release and spliceosome disassembly mechanisms.

The paper determines cryo-EM structures of yeast spliceosome B* complexes to elucidate the mechanism of the branching reaction during pre-mRNA splicing.

This study shows that microtubule acetylation via dTAT is essential for mechanosensation in Drosophila, affecting touch, gravity, and sound responses but not thermal sensing.