Cell polarity opposes Jak-STAT mediated Escargot activation that drives intratumor heterogeneity in a Drosophila tumor model
D. Chatterjee, F. Cong, X.-F. Wang, C. A. M. Costa, Y.-C. Huang, W.-M. Deng
The paper shows that cell polarity prevents Jak-STAT signaling from activating Escargot, reducing intratumor heterogeneity in a Drosophila tumor model.
bioRxiv · Dec 12, 2022 · PreprintCancer Biology