J. Mo

Wireless, Multimodal Monitoring of Organ Health Using 3D-Printed, Barbed, Bioresorbable Stretchable Microneedle Sensor Arrays

This paper introduces a wireless, 3D-printed microneedle sensor array for multimodal organ monitoring, capable of measuring metabolism, oxygenation, and electrophysiology with spatiotemporal resolution.

Epithelial IL-2 is critical for NK cell-mediated cancer immunosurveillance in mammary glands

The paper identifies epithelial IL-2 as critical for maintaining NK cell function in mammary glands, leading to improved immunosurveillance and prevention of tumor development.

Genetic insertion of mouse Myxovirus-resistance gene 1 increases innate resistance against both high and low pathogenic avian influenza virus by significantly decreasing replication in chicken DF1 cell line

This study introduces mouse Mx1 into chicken cells to enhance resistance against avian influenza, showing reduced viral replication and cytopathic effects.

Morphologic characterization and cytokine response of chicken bone-marrow derived dendritic cells to infection with high and low pathogenic avian influenza virus

This study examines the morphological changes and cytokine response of chicken bone-marrow derived dendritic cells infected with high and low pathogenic avian influenza viruses.

Unleashing the Power of NR4A1 Degradation as a Novel Strategy for Cancer Immunotherapy

This paper develops a PROTAC molecule (NR-V04) that degrades NR4A1, leading to tumor inhibition and immune modulation in melanoma.

The distinct roles of MSH2 and MLH1 in basal-like breast cancer and immune modulation

This study identifies distinct roles of MSH2 and MLH1 in basal-like breast cancer, showing MSH2 promotes metastasis while MLH1 enhances it, and reveals MSH2's role in immune modulation through IFNAR1 regulation.

Does the ratio of β-1,4-glucosidase (BG) to β-1,4-N-acetylglucosaminidase (NAG) indicate the relative resource allocation of soil microbes to C and N acquisition?

This study tests whether the BG:NAG ratio reflects microbial C vs N allocation by analyzing N fertilization effects and decomposition stages.

Zinc Sulfide-Based Hybrid Exosome-Coated Nanoplatform for Targeted Treatment of Glioblastoma in an Orthotopic Mouse Glioblastoma Model

This study develops HCQ@ZnS@exo@iRGD nanoparticles for glioblastoma treatment, showing selective damage to glioblastoma cells through combined autophagy inhibition and ROS production under light irradiation.

Diagnostic value of galactomannan in bronchoalveolar lavage fluid for chronic respiratory disease with pulmonary aspergillosis

This study evaluates the diagnostic value of bronchoalveolar lavage fluid galactomannan (BALF GM) for pulmonary aspergillosis in chronic respiratory disease, finding an optimal cut-off value of 0.485 with high sensitivity and specificity.

CRISPR/Cas9-mediated integration of large transgene into pig potential safe harbor

This study develops an efficient CRISPR/Cas9 method for integrating a large transgene cassette into the CEP112 locus in pigs, achieving successful expression of microbial enzymes in salivary glands.

Is microbial activity in tropical forests limited by phosphorus availability? Evidence from a tropical forest in China

This study investigates whether microbial activity in tropical forests is limited by phosphorus availability, finding that P addition increases soil respiration but suppresses litter decomposition due to organic carbon desorption.

Generation of a novel growth-enhanced and reduced environmental impact transgenic pig strain

This study generates transgenic pigs expressing microbial enzymes to enhance feed digestion and reduce nutrient emissions, showing improved growth and lower environmental impact.