H. Nie

Sophocarpine inhibits TRP channels to produce anti-pruritic and analgesic effects in a mouse model of inflammatory itch and pain

This study shows that sophocarpine inhibits TRPA1 and TRPV1 channels, reducing itch and pain in a mouse model of inflammatory conditions.

Horizontal transferred T-DNA and haplotype-based phylogenetic analysis uncovers the origin of sweetpotato

This study identifies two progenitors of sweetpotato using horizontal transferred T-DNA and haplotype-based phylogenetic analysis, revealing its origin from a reciprocal cross and whole genome duplication.

Blocking of EGFR Signaling is a Latent Strategy for the Improvement of Prognosis of HPV Induced Cancer

This study identifies EGFR downregulation as a mechanism by which HPV infection improves prognosis in cervical and head and neck cancers, suggesting EGFR inhibitors could be potential anti-HPV therapies.

Dynamic RNA 3' uridylation and guanylation during mitosis

The paper re-analyzes TAIL-seq data to reveal global RNA poly(A) tail terminal modifications during the mitotic cell cycle, suggesting their role in RNA regulation.

Isolation and long-term expansion of a single adult human renal epithelial cell with efficient kidney regeneration capacity

This study isolates and expands SOX9+ renal epithelial cells from adult humans, showing their ability to regenerate kidney tissue in mice.

QTL and genetic analysis controlling fiber quality traits using paternal backcross population in Upland cotton

This study identifies novel and validated QTLs for fiber quality traits in Upland cotton using a paternal backcross population and RILs, with some QTLs explaining over 10% of phenotypic variation.