J. Wen

Under constant infection by Sclerotinia sclerotiorum, BnaA03.WRKY28 interacts with BnaA09.VQ12 and takes precedence over phosphorylated BnWRKY33 to bind to the BnWRKY33 promoter, thereby weakening resistance but promoting branching.

This study shows that plants export 2-monopalmitin to arbuscular mycorrhizal fungi, supplying both fatty acyl and glyceryl moieties for fungal storage lipid synthesis.

This study investigates Fxr signaling and microbial bile salt metabolism in zebrafish intestines, revealing conserved pathways and Fxr roles in transcriptional programs.

This study uses target enrichment data to analyze phylogenetic conflicts in Caprifoliaceae, identifying ancient hybridization as a main source of discordance and recognizing Zabelioideae as a new subfamily.

This paper describes a catalase-based therapeutic for COVID-19 that reduces oxidative stress and cytokine production in human and animal models without toxicity.

This study generates and tests human embryonic stem cell-derived immunity-and-matrix-regulatory cells (IMRCs) for treating lung injury and fibrosis in mice, showing efficacy and safety.

This study investigates the impact of a GIPR variant on glucose homeostasis using a mouse model, finding altered intracellular trafficking and increased GIP sensitivity.

The paper shows insulin mobilizes GLUT4 from a TGN storage site via RAB10, revealing a non-specific TGN region for cargo transport.

The paper identifies MtYSL7 as a peptide transporter essential for symbiotic nitrogen fixation in Medicago truncatula, with evidence of its role in transition metal homeostasis.

The paper uses single-cell RNA-sequencing to identify IL-4/IL-13 as critical for IgE recall in peanut allergy and shows blocking this pathway prevents anaphylaxis.

This study shows that the Medicago truncatula YSL3 gene is essential for nitrogen fixation in root nodules by facilitating iron and zinc transport.

This study shows SPOP promotes ubiquitination and degradation of MyD88, suppressing innate immune responses and reducing susceptibility to Salmonella typhimurium infection.

This study investigates the role of PDH in Medicago truncatula by analyzing mutants, finding that MtPDH1 contributes to Tyr biosynthesis under stimulated shikimate pathway conditions.

This study shows that MtNAS2 is essential for iron delivery in Medicago truncatula nodules, supporting symbiotic nitrogen fixation.

This study shows that MtFPN2 in Medicago truncatula is essential for iron delivery to symbiosomes, supporting nitrogen fixation, but not for vascular iron transport.

The paper identifies MtMOT1.2 as a molybdate transporter essential for delivering molybdate to Medicago truncatula nodules for nitrogen fixation.

The paper shows that remorin and SYMREM1 stabilize LYK3 in membrane nanodomains, which is essential for successful symbiotic root infections in Medicago truncatula.

The paper identifies MtMOT1.3 as a molybdate transporter in Medicago truncatula root nodules essential for nitrogenase activity and symbiotic nitrogen fixation.