Author
T. Fu
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2018-2024 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 16 mutual co-author links11 papers
Recent·Most cited
Blocker-SELEX: A Structure-guided Strategy for Developing Inhibitory Aptamers Disrupting Undruggable Transcription Factor Interactions
Y. Wei, W. Tan, Q. Wu, T. Li, X. Liu, S. Zhang, Y. Hou, Y. Zhang, G. Luo, X. Zhu, Y. Tao, M. Fan, C. Sha, A. Lin, J. Qin, , T. Fu
This paper introduces Blocker-SELEX, a structure-guided method to design inhibitory aptamers that disrupt transcription factor interactions, demonstrating efficacy against SCAF4/SCAF8-RNAP2 and WDR5-MYC complexes.
bioRxiv · Jan 9, 2024 · PreprintBiochemistry
Molecular basis of Gabija anti-phage supramolecular assemblies
X. Yang, Z. Shen, Q. Lin, T. Fu
This study reveals the structure and function of the Gabija anti-phage system, showing GajA forms tetramers and GajAB forms octamers, with GajB enhancing DNA cleavage activity.
bioRxiv · Aug 7, 2023Immunology
Generating Electricity from Water Evaporation Through Microbial Biofilms
X. Liu, T. Ueki, H. Gao, T. L. Woodard, K. P. Nevin, T. Fu, S. Fu, L. Sun, D. R. Lovley, J. Yao
This paper demonstrates that engineered microbial biofilms can generate electricity from water evaporation, achieving power densities higher than non-biological materials.
bioRxiv · Dec 14, 2021Microbiology
The compound of baicalein, wogonin, and oroxylin-A inhibits EMT in A549 cell line via PI3K/AKT-TWIST1-glycolysis pathway
H. Cao, W. Zhou, X. Xian, S. Sun, P. Ding, C. Tian, F. Tian, C. Jiang, T. Fu, S. Zhao, J. Dai
This study identifies baicalein, wogonin, and oroxylin-A as active compounds in TFAE that inhibit EMT in A549 cells via the PI3K/AKT-TWIST1-glycolysis pathway.
bioRxiv · May 13, 2021Pharmacology & Toxicology
BnaA03.WRKY28, interacting with BnaA09.VQ12, acts as a brake factor of activated BnWRKY33-mediated resistance outburst against Sclerotinia sclerotiorum in Brassica napus
J. Tu, K. Zhang, F. Liu, Z. Wang, C. Zhuo, K. Hu, X. Li, J. Wen, B. Yi, J. Shen, C. Ma, T. Fu
Under constant infection by Sclerotinia sclerotiorum, BnaA03.WRKY28 interacts with BnaA09.VQ12 and takes precedence over phosphorylated BnWRKY33 to bind to the BnWRKY33 promoter, thereby weakening resistance but promoting branching.
bioRxiv · Jan 28, 2021 · PreprintPlant Biology
Shotgun lipidomics and mass spectrometry imaging unveil diversity and dynamics in lipid composition in Gammarus fossarum
T. Fu, O. Knittelfelder, O. Geffard, Y. Clement, E. Testet, N. Elie, D. Touboul, K. Abbaci, A. Shevchenko, J. Lemoine, A. Chaumot, A. Salvador, D. Degli-Esposti, S. Ayciriex
The paper uses shotgun lipidomics and mass spectrometry imaging to study lipid composition and spatial distribution in Gammarus fossarum, revealing dynamic lipid changes and sulfate-based lipids in oocytes.
bioRxiv · Dec 1, 2020Biochemistry
Co-evolution of Eukaryotic-like Vps4 and ESCRT-III Subunits in the Asgard Archaea
Z. Lu, T. Fu, T. Li, Y. Liu, S. Zhang, J. Li, J. Dai, E. V. Koonin, G. Li, H. Chu, M. Li
This study shows that Asgard archaea possess ESCRT complexes with eukaryotic-like structural and functional features, suggesting they are evolutionary precursors to eukaryotic ESCRTs.
bioRxiv · May 5, 2020 · PreprintMicrobiology
Differential RNA editing between epithelial and mesenchymal tumors impacts mRNA abundance in immune response pathways
T. Chan, T. Fu, J. H. Bahn, H.-I. Jun, J.-H. Lee, G. Quinones-Valdez, C. Cheng, X. Xiao
The paper identifies differential RNA editing between epithelial and mesenchymal tumors and shows its impact on immune response pathways through ILF3-mediated transcript stabilization.
bioRxiv · Mar 6, 2020Cancer Biology
LanD-like Flavoprotein-Catalyzed Aminovinyl-Cysteine Formation through Oxidative Decarboxylation and Cyclization of a Peptide at the C-Terminus
J. Liu, Y. Qiu, T. Fu, M. Li, Y. Li, Q. Yang, Z. Tang, H. Tang, G. Li, L. Pan, W. Liu
This paper identifies a dual activity in LanD-like flavoproteins for forming aminovinyl-cysteine residues through oxidative decarboxylation and cyclization of peptides.
bioRxiv · Feb 13, 2020 · PreprintBiochemistry
A low-cost DIY device for high resolution, continuous measurement of microbial growth dynamics
K. Sasidharan, A. S. Martinez-Vernon, J. Chen, T. Fu, O. Soyer
The paper introduces a low-cost, open-source DIY photometer, MicrobeMeter, for continuous microbial growth measurement, showing comparable accuracy to commercial devices.
bioRxiv · Sep 4, 2018 · PreprintMicrobiology