L. Liu

This study shows that knocking down GAS5 restores ox-LDL-induced autophagy dysfunction in endothelial cells by upregulating miR-26a.

The paper uses scRNA-seq to identify a profibrotic macrophage subtype in injured lung tissue, showing its role in fibrosis and potential as a therapeutic target.

The paper introduces a method combining aptamer probes and transcriptome sequencing to simultaneously analyze transcriptomes and proteomes of single cells, enabling cell type differentiation based on binding and expression patterns.

The paper uses a heteropolymer model with Hi-C data to study chromatin dynamics, finding that chromosome architecture determines spatiotemporal behavior and cell-to-cell variability.

This study uses SLIM to measure sperm cell thickness and refractive index, finding tail thickness down to 150 nm and refractive index up to 1.6 near the head.

The paper identifies 22 ancient whole genome duplications in Malpighiales, clustered around the Eocene-Paleocene Transition, supporting the hypothesis that WGDs aid plant survival during climatic upheavals.

The paper shows that FEA2, a CLAVATA receptor, responds to two different CLE peptides by signaling through distinct downstream effectors CT2 and CRN.

This study uses directed evolution to identify mutations that restore catalytic activity in a mutant enzyme, revealing how conformational dynamics are shaped by evolutionary selection.