M. Shah

Prophages block cell surface receptors to ensure survival of their viral progeny

The paper identifies a prophage protein that modulates pilus dynamics to prevent phage progeny destruction, enhancing survival through quorum sensing.

Genetic and karyotype divergence between parents affect clonality and sterility in hybrids

The paper investigates how genetic and karyotype divergence between parental fish lineages influences asexual gametogenesis and sterility in hybrids.

Prevalence of Slam-dependent hemophores in Gram-negative bacteria

The paper identifies HphAs as a new class of hemophores in Gram-negative bacteria, showing their structural similarity to hemophilin1 and dependence on Slam for secretion.

Childhood cancer mutagenesis caused by a domesticated DNA transposase

This study identifies PGBD5 as a primary mutator in medulloblastoma by showing it drives somatic DNA rearrangements in cerebellar progenitor cells.

Endothelial Cell-Specific Molecule-1 Inhibits Albuminuria in Diabetic Mice

This study shows that Esm-1 reduces albuminuria and podocyte injury in diabetic mice, possibly through inhibiting interferon signaling.

Sex Identification in Cattle, based on Amelogenin Gene

The paper uses the Amelogenin gene to identify cattle sex via PCR, showing that male DNA produces two bands and female DNA produces one band.

Genomic miscellany and allelic frequencies of Plasmodium falciparum msp-1, msp-2 and glurp in parasite isolates

This study analyzes genetic diversity and allelic frequencies of msp-1, msp-2, and glurp in P. falciparum isolates from Pakistan, finding high genetic diversity and significant correlation between MOI and parasite density for msp-2.

Correct block-design experiments mitigate temporal correlation bias in EEG classification

This paper refutes claims that block-design EEG experiments are biased by temporal correlation, showing that such correlation has minimal impact on classification accuracy when properly analyzed.

Megadalton-sized dityrosine aggregates of α-synuclein retain high degrees of structural disorder and internal dynamics.

This study examines megadalton-sized dityrosine aggregates of α-synuclein, revealing their structural disorder and dynamics, and their role in inhibiting classical amyloid formation.

Formin FHOD1 regulates the size of EPEC pedestals

This study shows that the formin FHOD1 regulates EPEC pedestal size by localizing to the pedestal base and its knockdown reduces pedestal surface area.

Indoleamine 2,3-dioxygenase-1 expressing aggregate bone marrow dendritic cell populations are associated with systemic T cell compartment changes in chronic myelomonocytic leukemia

This study examines the association between IDO1+ dendritic cell populations in CMML bone marrow and systemic T-cell changes, finding correlations with disease progression and immune suppression.

Actinobacillus utilizes a binding-protein dependent ABC transporter to acquire Vitamin B6

The paper identifies a Vitamin B6 uptake system in Actinobacillus using a binding-protein dependent ABC transporter, validated through structural and biochemical methods.

Insight towards the effect of the multibasic cleavage site of SARS-CoV-2 spike protein on cellular proteases

This study investigates how mutations in the multibasic cleavage site of SARS-CoV-2 spike protein affect interactions with host proteases, suggesting potential strategies for attenuating the virus and developing antivirals.

Fungal communities (Mycobiome) as potential ecological indicators within confluence stretch of Ganges and Yamuna Rivers, India

The paper analyzes fungal communities in sediment samples from the confluence of Ganges and Yamuna Rivers to assess their potential as ecological indicators of pollution and eutrophication.

Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia: A report from the TARGET initiative

The paper identifies genetic mechanisms of primary chemotherapy resistance in pediatric AML through whole-genome and transcriptome sequencing of treatment-failure cases.

Bacterial adaptation to diet is a key evolutionary force shaping Drosophila-Lactobacillus symbiosis

This study shows that bacterial adaptation to diet, not the host, drives the evolution of beneficial symbiosis between Drosophila and Lactobacillus.

Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors

This study identifies PGBD5 as an oncogenic DNA transposase in rhabdoid tumors, causing site-specific genomic rearrangements through PSS sequences and end-joining repair.