M. You

A portable electrochemical DNA sensor for sensitive and tunable detection of piconewton-scale cellular forces

This paper develops a portable electrochemical DNA sensor for detecting piconewton-scale cellular forces using CRISPR-Cas12a for enhanced sensitivity and tunable threshold forces.

Electrochemical DNA-based sensors for measuring cell-generated forces

This study develops electrochemical DNA-based sensors to measure cell-generated adhesion forces with high sensitivity and portability.

Multiplexed Sequential Imaging in Living Cells with Orthogonal Fluorogenic RNA Aptamer/Dye Pairs

This paper introduces seqFRIES, a method for multiplexed live-cell imaging using orthogonal RNA aptamer/dye pairs, achieving four-color imaging in ~20 minutes.

Targeted RNA Condensation in Living Cells via Genetically Encodable Triplet Repeat Tags

This study introduces a genetically encoded RNA tag to program RNA condensate formation and modulate RNA localization and function in living cells.

Gut microbiota assemblages of generalist predators are driven by local- and landscape-scale factors

This study examines how environmental factors shape spider gut microbiota composition using high-throughput sequencing, identifying local and landscape-scale drivers.

Genetically Encoded RNA-based Bioluminescence Resonance Energy Transfer (BRET) Sensors

This paper introduces genetically encoded RNA-based BRET sensors for real-time target detection in living cells, using a luciferase donor and RNA-based acceptor.

Contrasting roles of landscape compositions in shaping functional traits of arthropod community in subtropical vegetable fields

The paper evaluates how different habitat compositions affect functional traits of arthropod communities in subtropical vegetable fields, finding that forest and grassland habitats enhance functional diversity while non-brassica plantations and water bodies reduce it.

DNA metabarcoding of gut contents reveals key habitat and seasonal drivers of trophic networks involving generalist predators in agricultural landscapes

This study uses DNA metabarcoding to analyze gut contents of spiders in agricultural landscapes, revealing how environmental factors influence their trophic interactions and diet composition.

Live-Cell Imaging of (p)ppGpp with RNA-based Fluorescent Sensors

This paper develops RNA-based fluorescent sensors to directly image and measure (p)ppGpp in live bacterial cells, revealing cell-to-cell variation and dynamics under different nutritional conditions.

Mass cytometry reveals immunological response to radiation-induced cardiac fibrosis in mice

This study uses mass cytometry to analyze immunological changes in mice after radiation-induced cardiac fibrosis, finding increased macrophages and pro-fibrotic cytokines.

Landscape composition mediates suppression of major pests by natural enemies in conventional cruciferous vegetables

This study shows that increasing semi-natural habitats in conventional cruciferous vegetable fields improves pest suppression by natural enemies, with effects varying by pest type and landscape scale.

A comparative analysis reveals irreproducibility in searches of scientific literature

This study shows that search results from different databases vary by location and environment, highlighting the need for more consistent search practices in scientific research.

Quantifying Tensile Forces at Cell-Cell Junctions with a DNA-based Fluorescent Probe

This paper introduces a DNA-based fluorescent probe, DNAMeter, to quantify intercellular tensile forces through real-time imaging and fluorescence signal activation.