Author

N. Hingankar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Assay:proteomics· 3 Organism:human· 2 Assay:cryo-EM· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. Bhattacharya· 4 shared S. Deshpande· 4 shared D. Sok· 3 shared M. Y. Ansari· 3 shared P. Das· 3 shared S. Mukherjee· 3 shared G. Batra· 2 shared G. R. Medigeshi· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

J. Bhattacharya

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

High resolution cryo-EM structures of two potently SARS-CoV-2 neutralizing monoclonal antibodies of same donor origin that vary in neutralizing Omicron variants

C. F. Rencilin, M. Y. Ansari, A. Chatterjee, S. Deshpande, S. Mukherjee, R. Singh, S. Jayatheertha, P. M. Reddy, P. Das, N. Hingankar, D. Rathore, R. Varadarajan, J. Bhattacharya, S. Dutta

The paper presents high-resolution cryo-EM structures of two SARS-CoV-2 neutralizing mAbs from the same donor, showing differences in their binding to Omicron variants and conformational changes in the spike protein.

bioRxiv · Dec 3, 2022 · PreprintBiophysics

Ancestral SARS-CoV-2 driven antibody repertoire diversity in an unvaccinated individual correlates with expanded neutralization breadth

S. Deshpande, M. Y. Ansari, J. Sutar, P. Das, N. Hingankar, S. Mukherjee, P. Jayal, S. Singh, A. Anantharaj, J. Singh, S. Chattopadhyay, S. Raghavan, M. Gosain, S. Chauhan, S. Shrivas, , J. Bhattacharya

The paper examines antibody diversity in an unvaccinated SARS-CoV-2 infected individual, finding that post-vaccination neutralization breadth against Omicron variants is comparable to vaccinated individuals and breakthrough infections.

bioRxiv · Oct 19, 2022Immunology

A combination of potently neutralizing monoclonal antibodies isolated from an Indian convalescent donor protects against the SARS-CoV-2 delta variant

N. Hingankar, S. Deshpande, P. Das, Z. A. Rizvi, A. Burns, S. Barman, F. Zhao, M. Y. Ansari, S. Mukherjee, J. L. Torres, S. Chattopadhyay, F. Mehdi, J. Sutar, D. K. Rathore, K. Pargai, , J. Bhattacharya

This paper identifies two potent monoclonal antibodies from an Indian donor that neutralize SARS-CoV-2 variants including Delta, showing protection in a mouse model.

bioRxiv · Dec 25, 2021Immunology

Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer

R. Kumar, S. Deshpande, L. M. Sewall, G. Ozorowski, C. A. Cottrell, W.-H. Lee, L. G. Holden, S. T. Richey, A. Chandrawacar, K. Dhiman, A. Ashish, V. Kumar, S. Ahmed, N. Hingankar, N. Kumar, , J. Bhattacharya

This study shows that immunization with a thermostable HIV-1 clade C Env trimer induces potent autologous neutralizing antibodies in rabbits, with distinct epitope specificity compared to natural infection.

PLOS Pathogens · Apr 7, 2021Peer-reviewedImmunology