S. Chattopadhyay

The paper characterizes hCMV-specific memory T cells using single-cell transcriptomics and TCR analysis, identifying distinct functional subsets and their roles in immunity.

The paper examines antibody diversity in an unvaccinated SARS-CoV-2 infected individual, finding that post-vaccination neutralization breadth against Omicron variants is comparable to vaccinated individuals and breakthrough infections.

This study investigates the anticancer effects of Nigella sativa volatile oil on breast cancer cells and mice, showing synergistic anti-tumorigenic properties through miRNA regulation and apoptosis induction.

The paper evaluates k-means clustering for segmenting CT images of amoebic and pyogenic liver abscesses, finding better performance for pyogenic abscesses.

This study shows that cancer evolution can be inherently unpredictable, using agent-based models and patient-derived xenograft data to demonstrate chaotic clonal dynamics.

This study shows that Chikungunya virus (CHIKV) infection activates DNA damage response (DDR) pathways, increases DNA damage, and interacts with Chk2 and Chk1 to facilitate viral replication and cell cycle arrest.

This paper identifies two potent monoclonal antibodies from an Indian donor that neutralize SARS-CoV-2 variants including Delta, showing protection in a mouse model.

The paper isolates and characterizes five SARS-CoV-2 strains from India, showing variations in cytotoxicity and cell line permissiveness, and finds both Covaxin and Covishield vaccines neutralize all isolates effectively.

This study shows Telmisartan reduces Chikungunya virus infection in vitro and in vivo by modulating host pathways including AT1/PPAR-γ/MAPKs.

This study shows that MK2 and MK3 inhibition with CMPD1 reduces CHIKV infection by blocking actin remodeling and viral release, with potential for antiviral development.

This study uses quantitative proteomics to analyze SARS-CoV-2-infected hamster lung tissues, identifying differentially expressed proteins and pathways linked to disease pathogenesis and severity.

This study shows TRPV1 expression increases during T cell immunosuppression and contributes to elevated intracellular calcium levels, similar to immune activation.

This study investigates JEV prevalence and molecular epidemiology in pigs from three Indian states, finding higher infection rates in Manipur and identifying genotype III as dominant with specific mutations.

This study shows DHA improves steroid sensitivity in asthma models and is lower in steroid-insensitive asthmatics.

This study identifies IRGM as a negative regulator of interferon response by controlling cGAS-STING and RIG-I-MAVS pathways, linking its deficiency to autoimmunity and antiviral resistance.

This study shows TRPA1 is expressed in T cells and modulates calcium levels and activation markers during T cell stimulation.