R. Yuan

The paper analyzes single-cell transcriptomes of pig skin from six anatomical regions to characterize cellular heterogeneity and identify candidate genes for ECM accumulation.

This study shows RIP140 regulates HES1 expression and mitogenic activity in colon cancer cells, with implications for patient survival.

This study characterizes 52 patient-derived glioma cell lines with whole-genome sequencing, RNA-seq, and drug response screening, identifying three subtypes and their drug sensitivities and tumorigenic potential.

This study investigates CXCL4 signaling in human monocytes, identifying NF-κB and TBK1-JNK pathways and a potential role for TLR4, while noting challenges in isolating CXCL4's effects from endotoxin contamination.

This study shows CXCL4 enhances TLR8 responses in human monocytes by promoting inflammatory gene transcription and IL-1β production through TBK1-IRF5 signaling and chromatin remodeling.

The paper shows that high E2F transcription in cancer cells prevents cell cycle exit after DNA damage, leading to genomic instability and reduced drug sensitivity.

This study investigates how juvenile hormone (JH) regulates flight capability in Bactrocera dorsalis, finding that JH levels correlate with flight duration and distance, and that JH III treatment enhances flight performance.

This study investigates ibuprofen's effect on Pseudomonas aeruginosa biofilm development and quorum sensing, finding concentration-dependent inhibition of virulence factors and gene expression.

This study demonstrates that GII.17 virus-like particles (VLPs) can be produced and show protective potency against NoV GII.17 infection by blocking saliva histo-blood group antigen binding.

This study shows exogenous putrescine increases cyclic electron flow in cucumber under salt stress, improving ATP/NADPH ratios and reducing photoinhibition.