Author

S. Kopetz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Sorokin· 2 shared A. A. Machado· 1 shared A. Azhdarnia· 1 shared A. Dohlman· 1 shared A. Jeschko· 1 shared A. K. Ghosh· 1 shared A. K. Singh· 1 shared A. T. Raman· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. Sorokin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The oncogenic role of Streptococcus gallolyticus subsp. gallolyticus is linked to activation of multiple cancer-related signaling pathways

E. Pasquereau-Kotula, G. Nigro, F. Dingli, D. Loew, P. Poullet, Y. Xu, S. Kopetz, J. Davis, L. Peduto, C. Robbe-Masselot, P. Sansonetti, P. Trieu-Cuot, S. Dramsi

This study shows that SGG UCN34 promotes colon cancer by activating multiple cancer-related signaling pathways through proteomic and phosphoproteomic analyses in mice and human tumors.

bioRxiv · Feb 17, 2023 · PreprintMicrobiology

Combined KRASG12C and SOS1 inhibition enhances and extends the anti-tumor response in KRASG12C-driven cancers by addressing intrinsic and acquired resistance

V. Thatikonda, H. Lu, S. Jurado, K. Kostyrko, C. A. Bristow, K. Bosch, N. Feng, S. Gao, D. Gerlach, M. Gerlach, S. Lieb, A. Jeschko, A. A. Machado, E. D. Marszalek, M. Mahendra, , M. H. Hofmann

This study shows that combining KRASG12C and SOS1 inhibitors improves anti-tumor response and delays resistance in KRASG12C-driven cancers.

bioRxiv · Jan 23, 2023Cancer Biology

Chromatin Remodeling in Patient-Derived Colorectal Cancer Models

K. Xiang, E. Wang, G. Rupprecht, J. Mantyh, M. Negrete, G. Sanati, C. Hsu, P. Randon, A. Dohlman, K. Kretzschmar, N. Giroux, S. Ding, L. Wang, J. Prado, Q. Huang, , X. Shen

This study compares chromatin remodeling in colorectal cancer patient-derived models and identifies transcription factors driving differences in growth and drug response.

bioRxiv · Jul 24, 2022Cancer Biology

Chromatin State Dynamics Confers Specific Therapeutic Strategies in Enhancer Subtypes of Colorectal Cancer

E. Orouji, A. T. Raman, A. K. Singh, A. Sorokin, E. Arslan, A. K. Ghosh, J. Schulz, C. J. Terranova, M. Tang, M. Maitituoheti, S. C. Callahan, K. J. Tomczak, Z. Jiang, J. S. Davis, S. Ghosh, , K. Rai

This study identifies enhancer subtypes in colorectal cancer through epigenomic analysis and proposes targeted therapeutic strategies based on these subtypes.

bioRxiv · Sep 4, 2020Cancer Biology