Author

S. Richards

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Microbiology· 2 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2

Frequent Co-Authors

S. W. Schaeffer· 2 shared Z. L. Fuller· 2 shared A. Aebi· 1 shared A. Graff Meyer· 1 shared A. K. Green· 1 shared A. Lopez-Ezquerra· 1 shared A. Moser· 1 shared A. Osmont· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersEvolutionary Biology

S. W. Schaeffer

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Author profile →

7 papers

Recent·Most cited

Genomics of Natural Populations: Gene Conversion Events Reveal Selected Genes within the Inversions of Drosophila pseudoobscura

S. W. Schaeffer, S. Richards, Z. L. Fuller

This study identifies selected genes within chromosomal inversions of Drosophila pseudoobscura by analyzing gene conversion events and their association with outlier loci.

bioRxiv · Aug 15, 2022Evolutionary Biology

Loss of hepatic Lgr4 and Lgr5 promotes nonalcoholic fatty liver disease

E. Saponara, C. Penno, M. L. Matadamas Guzman, V. Brun, B. Fischer, M. Brousseau, Z.-Y. Wang, P. ODonnell, J. Turner, A. Graff Meyer, L. Bollepalli, G. dArio, G. Roma, W. Carbone, V. Orsini, , H. Ruffner

This study shows that deleting Lgr4/5 in mouse livers disrupts Wnt/β-catenin signaling, leading to fatty liver disease and fibrosis.

bioRxiv · Nov 22, 2021Physiology

Virucidal activity of CPC-containing oral rinses against SARS-CoV-2 variants and are active in the presence of human saliva

E. R. Anderson, E. I. Patterson, S. Richards, A. K. Green, S. Mukherjee, M. Hoptroff, G. Hughes

This study evaluates CPC-containing mouthwashes' virucidal activity against SARS-CoV-2 variants, showing significant inactivation even in the presence of human saliva.

bioRxiv · Aug 5, 2021Microbiology

Discovery and Development of Human SARS-CoV-2 Neutralizing Antibodies using an Unbiased Phage Display Library Approach

X. Cao, J. Maruyama, H. Zhou, L. Kerwin, R. Sattler, J. T. Manning, S. Johnson, S. Richards, Y. Li, W. Shen, B. Blair, N. Du, K. Morais, K. Lawrence, L. Lu, , R. D. Allen

This study identifies and develops human SARS-CoV-2 neutralizing antibodies using a phage display library, showing their efficacy in vivo against the virus.

bioRxiv · Sep 27, 2020 · PreprintMicrobiology

TMIGD1, a putative tumor suppressor, induces G2-M cell cycle checkpoint arrest in colon cancer cells

K. O. De La Cena, R. Ho, R. Amraei, N. Woolf, J. Y. Tashjian, Q. Zhao, S. Richards, J. Walker, J. Huang, V. Chitalia, N. Rahimi

This study identifies TMIGD1 as a tumor suppressor that arrests the cell cycle in colon cancer cells and is downregulated in human CRC, correlating with poor survival.

bioRxiv · Jun 6, 2020Cancer Biology

Extensive recombination suppression and chromosome-wide differentiation of a segregation distorter in Drosophila

Z. L. Fuller, S. A. Koury, C. J. Leonard, R. E. Young, K. Ikegami, J. Westlake, S. Richards, S. W. Schaeffer, N. Phadnis

The paper analyzes the evolutionary dynamics of a segregation distorter in Drosophila pseudoobscura, finding that it persists due to suppressed recombination and epistatic selection.

bioRxiv · Dec 21, 2018 · PreprintEvolutionary Biology

Hemimetabolous genomes reveal molecular basis of termite eusociality

M. C. Harrison, E. Jongepier, H. M. Robertson, N. Arning, T. Bitard-Feildel, H. Chao, C. P. Childers, H. Dinh, H. Doddapaneni, S. Dugan, J. Gowin, C. Greiner, Y. Han, H. Hu, D. S. T. Hughes, , E. Bornberg-Bauer

The paper compares genomes and transcriptomes of termites and cockroaches to identify molecular mechanisms underlying termite eusociality, finding parallels and differences with Hymenoptera.

bioRxiv · Nov 15, 2017Evolutionary Biology