Author

X.-L. Feng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

D.-D. Yu· 2 shared J.-B. Han· 2 shared Y.-T. Zheng· 2 shared C. Meng· 1 shared D. Tian· 1 shared D. Yu· 1 shared G. Cheng· 1 shared H. Peng· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

D.-D. Yu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2

L. Xu, D. Yu, M. Xu, L.-X. Yang, Q.-C. Zou, X.-L. Feng, M.-H. Li, N. Sheng, Y.-G. Yao

This study identifies BTN3A2 as a primate-specific gene that inhibits SARS-CoV-2 infection by reducing ACE2 expression and blocking viral attachment.

bioRxiv · Jan 13, 2024Cell Biology

Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2

S. Sun, Y. Cai, T.-Z. Song, Y. Pu, L. Cheng, H. Xu, C. Meng, Y. Lin, J. Sun, S. Zhang, Y. Gao, J.-B. Han, X.-L. Feng, D.-D. Yu, Y. Zhu, , H. Peng

This study develops an IFN-armed RBD dimer vaccine that induces strong neutralizing antibodies and T cell responses, offering complete protection against SARS-CoV-2 in rhesus macaques with a single dose.

bioRxiv · May 12, 2021Immunology

A recombinant receptor-binding domain in trimeric form generates completely protective immunity against SARS-CoV-2 infection in nonhuman primates

L. Yang, D. Tian, J.-b. Han, W. Fan, Y. Zhang, Y. Li, W. Sun, Y. Wei, X. Tian, D.-d. Yu, X.-l. Feng, G. Cheng, Y.-t. Zheng, Y. Bi, W. Liu

This study develops a trimeric RBD vaccine that induces long-term immunity and complete protection against SARS-CoV-2 in nonhuman primates.

bioRxiv · Mar 30, 2021Immunology