J. Huang

This paper introduces a high-throughput method for drug screening using tumor organoids and identifies effective drugs for ovarian cancer within a week of surgery.

This study examines how intra- and intermolecular triplet-state quenching affects photobleaching and photoswitching in fluorophores, showing competition between these processes and identifying new roles for intramolecular quenchers.

This study identifies reduced diffusional conductance to CO2 as the main factor limiting photosynthesis in salt-stressed rice leaves.

The paper identifies and validates single-copy gene markers for phylogenomic studies in ray-finned fishes using comparative genomics and empirical testing across 83 species.

This study identifies 208 imprinted genes in rice, showing limited transposable element association, intraspecific variation, and conservation of imprinting at some loci across plant species.

This study identifies a Calcineurin-FoxO-MuRF1 signaling pathway that mediates Ca2+ overload-induced myofibril degradation in cardiomyocytes using zebrafish models.

This study shows PD-1 inhibits T cell activation by preferentially dephosphorylating CD28 over TCR, revealing CD28 as a primary target for PD-1-mediated suppression.