L. Long

Mechanically stimulated osteocytes maintain tumor dormancy in bone metastasis of non-small cell lung cancer by releasing small extracellular vesicles

This study shows that mechanically stimulated osteocytes release extracellular vesicles containing microRNAs that inhibit NSCLC cell proliferation and bone metastasis progression.

Pathology of natural infection with highly pathogenic avian influenza virus (H5N1) clade 2.3.4.4b in wild terrestrial mammals in the United States in 2022

The paper reports the first cases of H5N1 avian influenza in wild mammals in the US, showing neurological symptoms and lesions linked to bird-to-mammal spillover.

A Toxin-Antidote Selfish Element Increases Fitness of its Host

The paper shows a toxin-antidote element in C. elegans provides a fitness benefit to hosts, explaining its prevalence despite minimal gene drive.

Direct photoresponsive inhibition of a p53-like transcription activation domain in PIF3 by Arabidopsis phytochrome B

This study identifies a p53-like transcription activation domain in PIF3 and shows that PHYB binding inhibits its activity, revealing a photoresponsive transcriptional switch in Arabidopsis.

Increased light availability enhances tolerance against ocean acidification stress in Halimeda opuntia

Increased light availability enhances stress resistance in Halimeda opuntia by the accumulation of soluble organic molecules and enzyme-driven activities to alleviate ocean acidification stress.

Circulating BMP9 protects the pulmonary endothelium during inflammation-induced lung injury in mice

This study shows that BMP9 protects pulmonary endothelium during inflammation-induced lung injury and that exogenous BMP9 can prevent lung injury in mice.

A potent antibiofilm agent inhibits and eradicates mono- and multi-species biofilms

This paper identifies elasnin as a potent antibiofilm agent that inhibits mono- and multi-species biofilms with low toxicity and resistance risk.

Automated measurement of long-term bower behaviors in Lake Malawi cichlids using depth sensing and action recognition

This paper develops an automated system to measure bower construction behaviors in Lake Malawi cichlids using depth sensing and action recognition, revealing non-uniform and repeatable behaviors across species and hybrids.

Evolution of Yin and Yang isoforms of a chromatin remodeling subunit results in the creation of two genes

This study shows that the nurf-1 gene in C. elegans split into two isoforms, Yin and Yang, which have opposing roles in gametogenesis and led to the creation of two separate genes.

In Vitro and In Vivo activity of a novel catheter lock solution against bacterial and fungal biofilms

This paper evaluates a new antimicrobial catheter lock solution (ACL) against bacterial and fungal biofilms in vitro and in vivo, showing significant reduction in biofilm formation and eradication.