Author

J. Weng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 2 Biochemistry· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

S. Xu· 2 shared Z. Zhang· 2 shared A. M. Hockenberry· 1 shared B. Han· 1 shared C. Liu· 1 shared D. Jackson· 1 shared D. Wang· 1 shared E. G. Iturbe· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

S. Xu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The maize PLASTID TERMINAL OXIDASE (PTOX) gene controls the carotenoid content of kernels.

Y. Nie, H. Wang, G. Zhang, H. Ding, B. Han, L. Liu, J. Shi, J. Du, X. Li, Y. Zhao, X. Zhang, C. Liu, J. Weng, X. Zhao, G. Pan, , Z. Zhang

This study identifies ZmPTOX1 as a key gene for carotenoid biosynthesis in maize kernels, showing that its disruption reduces carotenoid content while overexpression increases it, particularly beta-carotene.

bioRxiv · Mar 13, 2023 · PreprintPlant Biology

Effect of GDF15 on acetaminophen (APAP)-induced liver injury in mice

P. Jiang, Z. Liu, T. Fang, Z. Zhang, D. Wang, S. Xu, J. Weng

This study investigates the role of GDF15 in APAP-induced liver injury in mice, finding no significant ameliorative effect from overexpression or supplementation of GDF15.

bioRxiv · Mar 13, 2022 · PreprintPharmacology & Toxicology

Insight into the mechanism of H+-coupled nucleobase transport

J. Weng, X. Zhou, P. Wiriyasermkul, Z. Ren, X. Yan, K. Chen, E. G. Iturbe, M. Zhou, M. Quick

The paper reports the structure and function of PurTCp, a NAT family transporter from Colwellia psychrerythraea, showing it transports purines via H+-dependent mechanism and identifies a critical aspartate residue.

bioRxiv · Dec 20, 2021 · PreprintBiochemistry

KLF2 is a therapeutic target for COVID-19 induced endothelial dysfunction

S. Xu, S. Luo, X. Zheng, J. Weng

This study shows that activating KLF2 reduces endothelial dysfunction in COVID-19 by decreasing monocyte adhesion and inflammation.

bioRxiv · Feb 20, 2021 · PreprintPharmacology & Toxicology

Microbiota-derived metabolites inhibit Salmonella virulent subpopulation development by acting on single-cell behaviors

A. M. Hockenberry, G. Micali, G. Takacs, J. Weng, W.-D. Hardt, M. Ackermann

This study shows microbiota-derived short-chain fatty acids reduce Salmonella virulent subpopulation frequency by slowing their growth, not by repressing SPI-1 expression at the single-cell level.

bioRxiv · Feb 14, 2021Microbiology