Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
T. Skrzypczak, M. Pochylski, M. Rapp, P. Wojtaszek, A. Kaprowicz-Maluski
This study examines how Nicotiana tabacum BY-2 cells adapt to high osmolarity by analyzing their viscoelastic properties using micro-mechanical imaging techniques.
bioRxiv · Apr 29, 2024 · PreprintPlant Biology
J. Sprooten, I. Vanmeerbeek, A. Datsi, J. Govaerts, D. Borras, S. Naulaerts, R. Laureano, A. Calvet, M. Kuballa, M. Sabel, M. Rapp, C. Knobbe-Thomsen, P. Liu, L. Zhao, O. Kepp, , A. D. Garg
This paper shows that DC vaccines can activate PD-L1+ macrophages in lymph nodes and tumors, creating an immunosuppressive circuit that limits their effectiveness, but this can be overcome by combining with PD-L1 blockade.
bioRxiv · Mar 14, 2023Immunology
N. T. Johansen, M. Bonaccorsi, T. Bengtsen, A. H. Larsen, F. G. Tidemand, M. C. Pedersen, P. Huda, J. Berndtsson, T. Darwish, N. R. Yepuri, A. Martel, T. Pomorski, A. Bertarello, M. S. Sansom, M. Rapp, , L. Arleth
This study investigates the conformational dynamics of CorA, revealing Mg2+-dependent conformational equilibria and dynamic behavior through SANS, MD simulations, and NMR.
bioRxiv · Aug 20, 2021Biophysics
G. Cerutti, M. Rapp, Y. Guo, F. Bahna, J. Bimela, E. R. Reddem, J. Yu, P. Wang, L. Liu, Y. Huang, D. D. Ho, P. D. Kwong, Z. Sheng, L. Shapiro
This study reports cryo-EM structures of two SARS-CoV-2 neutralizing antibodies bound to spike proteins of emerging variants, showing they retain potency despite RBD mutations.
bioRxiv · Feb 21, 2021Biochemistry
M. Rapp, Y. Guo, E. R. Reddem, L. Liu, P. Wang, J. Yu, G. Cerutti, J. Bimela, F. Bahna, S. Mannepalli, B. Zhang, P. D. Kwong, D. D. Ho, L. Shapiro, Z. Sheng
The paper determines structures of three VH1-2-derived antibodies in complex with SARS-CoV-2 spike, revealing modular recognition mechanisms and conformational changes.
bioRxiv · Jan 11, 2021Immunology
G. Cerutti, Y. Guo, T. Zhou, J. Gorman, M. Lee, M. Rapp, E. R. Reddem, J. Yu, F. Bahna, J. Bimela, Y. Huang, P. S. Katsamba, L. Lihong, M. S. Nair, R. Rawi, , L. Shapiro
This study identifies potent SARS-CoV-2 neutralizing antibodies targeting the N-terminal domain (NTD) and reveals they bind a common supersite on the spike protein.
bioRxiv · Jan 10, 2021Biochemistry
L. Liu, P. Wang, M. S. Nair, J. Yu, M. Rapp, Q. Wang, Y. Luo, J. F.-W. Chan, V. Sahi, A. Figueroa, X. V. Guo, G. Cerutti, J. Bimela, J. Gorman, T. Zhou, , D. D. Ho
The paper isolates and characterizes 61 SARS-CoV-2-neutralizing monoclonal antibodies from infected patients, identifying potent antibodies targeting multiple epitopes on the spike protein.
Nature · Jul 22, 2020Peer-reviewedMicrobiology
K. Wuertz-Kozak, M. Roszkowski, E. Cambria, A. Block, G. A. Kuhn, T. Abele, W. Hitzl, D. Driesslein, R. Mueller, M. Rapp, I. M. Mansuy, E. M. J. Peters, P. M. Wippert
This study examines the effects of early life stress on bone homeostasis in mice and humans, finding catabolic bone changes associated with stress-related factors.
bioRxiv · Jul 21, 2020Physiology
A. J. Noble, V. P. Dandey, H. Wei, J. Brasch, J. Chase, P. Acharya, Y. Z. Tan, Z. Zhang, L. Y. Kim, G. Scapin, M. Rapp, E. T. Eng, W. J. Rice, A. Cheng, C. J. Negro, , B. Carragher
This study uses fiducial-less tomography to analyze cryoEM grids and finds that 90% of particles are adsorbed to air-water interfaces, impacting protein structure and single particle analysis.
bioRxiv · Dec 11, 2017Biophysics