Author

O. Rom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pathology· 3 Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:metabolomics· 2

Frequent Co-Authors

A. C. Finney· 2 shared A. Yurdagul· 2 shared J. G. Traylor· 2 shared Y. E. Chen· 2 shared A. Ghrayeb· 1 shared A. W. Orr· 1 shared B. Agranovich· 1 shared B. Cai· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

A. C. Finney

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

CD14 Blockade Does Not Improve Outcomes of Deep Vein Thrombosis Following Inferior Vena Cava Stenosis in Mice

N. Pandey, H. Kaur, L. Chandaluri, S. K. Anand, H. Chokhawala, T. Magdy, K. Stokes, A. W. Orr, O. Rom, N. Dhanesha

This study investigates whether CD14 blockade improves DVT outcomes after IVC stenosis in mice, finding no significant effect on thrombus weight, incidence, or neutrophil recruitment.

bioRxiv · Jan 10, 2024 · PreprintPathology

Cholesterol-associated Locus EHBP1 Protects against NASH Fibrosis

F. Ma, M. Longo, X. Huang, M. Meroni, S. Prakash, E. Paolini, D. Bhattacharya, S. Wang, X. Wang, S. Mughal, S. Hussain, S. Anand, A. Yurdagul, O. Rom, P. Dongiovanni, , B. Cai

This study identifies EHBP1 as a protective locus against NASH fibrosis by regulating cholesterol metabolism and interacting with other cholesterol-related genes.

bioRxiv · Jul 8, 2023 · PreprintPathology

Fatty liver-mediated glycine restriction impairs glutathione synthesis and causes hypersensitization to acetaminophen

A. Ghrayeb, B. Agranovich, D. Peled, A. C. Finney, I. Abramovitch, J. Fernandez Garcia, J. G. Traylor, S. Drucker, S. I. Fernandes, N. Weissman, Y. E. Chen, O. Rom, I. Mor, E. Gottlieb

This study shows fatty liver reduces glycine, impairing glutathione synthesis and increasing sensitivity to acetaminophen toxicity in mice.

bioRxiv · Jan 16, 2023 · PreprintBiochemistry

Spatially Resolved Metabolites in Stable and Vulnerable Human Atherosclerotic Plaques Identified by Mass Spectrometry Imaging

E. H. Seeley, Z. Liu, S. Yuan, C. Stroope, E. D. Cockerham, N. Rashdan, A. C. Finney, D. Kumar, S. Das, B. Razani, W. Liu, J. G. Traylor, O. Rom, C. B. Pattillo, A. Yurdagul

This study identifies spatially resolved metabolite differences between stable and unstable human atherosclerotic plaques using mass spectrometry imaging and RNA-seq integration.

bioRxiv · May 30, 2022 · PreprintPathology

IDOL deficiency inhibits cholesterol-rich diet-induced atherosclerosis in rabbits

t. koike, y. koike, y. guo, d. yang, j. song, j. xu, x. zhao, t. zhu, r. li, b. wen, D. Sun, o. rom, R. Han, j. fan, m. t. Garcia-Barrio, , y. e. chen

This study shows that IDOL deficiency reduces atherosclerosis in rabbits fed a high-cholesterol diet by improving lipid metabolism and bile acid excretion.

bioRxiv · May 3, 2022Physiology