Author

B. Wen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Animal Behavior & Cognition· 1 Cancer Biology· 1 Ecology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Assay:proteomics· 6 Research Focus:cancer & tumor microenvironment· 4 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3

Frequent Co-Authors

Q. Wang· 3 shared D. Sun· 2 shared E.-M. Li· 2 shared J. Zhang· 2 shared L.-D. Liao· 2 shared L.-Y. Xu· 2 shared X. Qu· 2 shared Y. Liu· 2 shared

Activity by Year

2018-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersCell Biology

Q. Wang

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Author profile →

10 papers

Recent·Most cited

Dual Targeting of STING and PI3Kγ Eliminates Regulatory B Cells to Overcome STING Resistance for Pancreatic Cancer Immunotherapy

C. LI, S. Mao, H. Zhao, M. He, M. Wang, Z. Liu, H. Wen, Z. Yu, B. Wen, M. Djibo, J. Tao, Y. Bu, W. Gao, D. Sun

This paper develops a dual-targeting compound that eliminates regulatory B cells and overcomes STING resistance in pancreatic cancer, improving immunotherapy outcomes.

bioRxiv · Feb 14, 2024 · PreprintPharmacology & Toxicology

CHAF1A promotes the translesion DNA synthesis pathway in response to DNA replication stress

B. Wen, H.-X. Zheng, D.-X. Deng, Z.-D. Zhang, J.-H. Heng, L.-D. Liao, L.-Y. Xu, E.-M. Li

This study identifies CHAF1A as a novel regulator of the translesion DNA synthesis pathway, enhancing cancer cell survival under DNA replication stress.

bioRxiv · Apr 21, 2023 · PreprintCell Biology

MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization

Y. Zhang, X. Cao, Z. Gao, X. Ma, Q. Wang, X. Cai, Y. Zhang, Z. Zhang, G. Wei, B. Wen

The paper shows MATR3 and antisense LINE1 RNAs form a meshwork that organizes chromatin, and their disruption causes chromatin reorganization.

bioRxiv · Sep 13, 2022Cell Biology

Spike-specific CXCR3+ TFH cells play a dominant functional role in supporting antibody responses in SARS-CoV-2 infection and vaccination

J. Zhang, R. He, B. Liu, X. Zheng, Q. Wu, B. Wen, Q. Wang, Z. Liu, F. Chang, Y. Hu, T. Xie, Y. Liu, J. Chen, J. Yang, S. Teng, , X. Qu

This study identifies spike-specific CXCR3+ TFH cells as key drivers of long-term antibody responses in SARS-CoV-2 infection and vaccination.

bioRxiv · Aug 9, 2022 · PreprintImmunology

IDOL deficiency inhibits cholesterol-rich diet-induced atherosclerosis in rabbits

t. koike, y. koike, y. guo, d. yang, j. song, j. xu, x. zhao, t. zhu, r. li, b. wen, D. Sun, o. rom, R. Han, j. fan, m. t. Garcia-Barrio, , y. e. chen

This study shows that IDOL deficiency reduces atherosclerosis in rabbits fed a high-cholesterol diet by improving lipid metabolism and bile acid excretion.

bioRxiv · May 3, 2022Physiology

LOXL2-dependent deacetylation of aldolase A induces metabolic reprogramming and tumor progression

J.-W. Jiao, X.-H. Zhan, J.-J. Wang, L.-X. He, Z.-C. Guo, X.-E. Xu, L.-D. Liao, X. Huang, B. Wen, Y.-W. Xu, H. Hu, G. Neufeld, Z.-J. Chang, K. Zhang, L.-Y. Xu, E.-M. Li

This study identifies LOXL2 and its variant L2{Delta}13 as deacetylases that reprogram tumor metabolism by deacetylating aldolase A, promoting tumor progression.

bioRxiv · Mar 6, 2022Cell Biology

Microscaled Proteogenomic Methods for Precision Oncology

S. Satpathy, E. J. Jaehnig, K. Krug, B.-J. Kim, A. B. Saltzman, D. Chan, K. R. Holloway, M. Anurag, C. Huang, P. Singh, A. Gao, N. Namai, Y. Dou, B. Wen, S. Vasaikar, , M. J. Ellis

This study develops microscaled proteogenomic methods for cancer analysis, showing treatment response and resistance mechanisms in ERBB2-positive breast cancers.

bioRxiv · Oct 9, 2019Cancer Biology

Sensitivity in the antioxidant system of discus fish (Symphysodon spp.) to cold temperature: evidence for species-specific cold resistance

s. r. jin, b. wen, Z. Chen, j. z. gao, l. wang, y. liu, h. p. liu

This study compares cold resistance in two discus fish species using antioxidant indexes, finding interspecific variation linked to environmental adaptation.

bioRxiv · Aug 29, 2019 · PreprintEcology

Androgen-dmrt1 positive feedback programs the rice field eel (Monopterus albus) sex transdifferentiation

B. Wen, X. Qu, L. Pan, J. Gao, H. Wu, Q. Wang

This study identifies androgen-dmrt1 positive feedback as a mechanism driving sex reversal in rice field eel by analyzing gene regulation and enzyme expression.

bioRxiv · Apr 7, 2019 · PreprintAnimal Behavior & Cognition

Improvements to the rice genome annotation through large-scale analysis of RNA-Seq and proteomics datasets

Z. Ren, D. Qi, N. Pugh, K. Li, B. Wen, R. Zhou, S. Xu, S. Liu, A. R. Jones

The paper improves rice genome annotation by analyzing RNA-Seq and proteomics data, identifying 692 genomic loci with potential annotation updates.

bioRxiv · Apr 12, 2018Plant Biology