Author

R. Flavell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

D. M. Wilson· 2 shared J. Blecha· 2 shared M. Ohliger· 2 shared O. Rosenberg· 2 shared A. Alanizi· 1 shared A. Maminska· 1 shared A. Odainic· 1 shared A. Roers· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

D. M. Wilson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Chemoenzymatic syntheses of fluorine-18-labeled disaccharides from FDG yield potent sensors of living bacteria in vivo

A. Sorlin, M. Lopez Alvarez, S. Rabbitt, A. Alanizi, B. Shuere, K. N. Bobba, J. Blecha, S. Sakhamuri, M. Evans, K. J. Bayles, R. Flavell, O. Rosenberg, R. Sriram, T. Desmet, B. Nidetzky, , D. M. Wilson

This paper develops chemoenzymatic methods to synthesize [18F]-labeled disaccharides from FDG, which detect bacteria in vivo by their specific glycan incorporation.

bioRxiv · May 20, 2023 · PreprintMicrobiology

Suppression of systemic T cell immunity to viral infection during liver injury is prevented by inhibition of interferon and IL-10 signaling

P. C. Hackstein, J. Spitzer, K. Symeonidis, H. Horvatic, T. Bedke, B. Steglich, L. Assmus, A. Odainic, N. Kessler, S. Klein, M. Beyer, R. Schmithausen, E. Latz, C. Kurts, J. Trebicka, , Z. Abdullah

The paper shows that liver injury suppresses systemic T cell immunity to viral infection, which can be reversed by inhibiting interferon and IL-10 signaling in preclinical models and human patients.

bioRxiv · Jul 21, 2022 · PreprintImmunology

A hierarchical GBP network promotes cytosolic LPS recognition and sepsis

J. D. MacMicking, E. Park, B. Kim, P. Kumar, K. Tretina, A. Maminska, W. M. Philbrick, R. Flavell

The paper identifies a hierarchical GBP network that regulates cytosolic LPS recognition and sepsis by coordinating caspase-11 and gasdermin D functions.

bioRxiv · Aug 25, 2021 · PreprintImmunology

Cyclic gallium-68 labeled peptides for specific detection of human angiotensin-converting enzyme 2

M. Parker, J. Blecha, O. Rosenberg, M. Ohliger, R. Flavell, D. M. Wilson

This paper develops 68Ga-labeled cyclic peptides derived from ACE2 inhibitor DX600 to detect ACE2 expression in vivo, showing specific binding in organs affected by SARS-CoV-2.

bioRxiv · Dec 15, 2020Biochemistry

Map3k2-Regulated Intestinal Stromal Cells (MRISC) Define a Distinct Sub-cryptic Stem Cell Niche for Damage Induced Wnt Agonist R-spondin1 Production

N. Wu, H. Sun, X. Zhao, L. Chen, Y. Qi, Y. Han, X.-n. Liu, C. Gao, Q. Wang, L. He, X. Niu, Z. Liu, H. Li, Y. A. Zeng, M. Roulis, , B. Su

The paper identifies MRISC cells as a novel intestinal stem cell niche that produces R-spondin1 via Map3k2 signaling to promote intestinal regeneration after damage.

bioRxiv · Oct 21, 2019 · PreprintCell Biology