S. Sharma

This study shows that the LSD1 inhibitor SP-2577 enhances anti-tumor immunity and PD-L1 expression in SWI/SNF-mutated ovarian cancer models.

This study uses carnivores in India to assess conservation priorities by integrating ecological, social, and economic factors, identifying gaps in current protected areas and suggesting alternative strategies.

This paper identifies DINO, a long noncoding RNA, as a mediator of TP53 stabilization in HPV16 E7 expressing cells, linking E7 to increased TP53 levels and metformin sensitivity.

This study characterizes VTL genes in hexaploid wheat, showing their expression patterns under metal stress and their potential role in metal homeostasis.

This study identifies mangiferin, a compound from mango trees, as a potential anticancer drug targeting CDK4, which is linked to cancer survival rates and expression patterns in GBM, LGG, and SARC.

This study analyzes land cover changes and forest fragmentation in Nepal's Dhorpatan Hunting Reserve using Landsat data from 1993 to 2018, finding increased forest and snow areas and decreased grassland and agriculture.

The paper investigates natural variation in aliphatic glucosinolate accumulation in Arabidopsis thaliana by analyzing genetic and metabolic diversity across ecotypes.

This study shows rats can act altruistically by voluntarily distressing themselves to help others without expecting rewards.

The paper screens CYP8B1 gene sequences across 200+ species to identify relaxed selection linked to dietary changes in birds and mammals.

This paper introduces a non-radioactive mass assay to measure phosphatidylinositol-5-phosphate (PI5P) levels in Drosophila cells and tissues with high sensitivity.

This paper shows that sustained trypsin exposure induces cells to transition into a reversible stem-like state, enabling transdifferentiation and altering cellular behavior.

The paper uses metabolomic profiling and bioinformatics to identify metabolite biomarkers and genes involved in cold-induced sweetening in potato cultivars.

This study shows that applying KNO3 improves salinity tolerance in Stevia rebaudiana by maintaining ion balance under moderate to high salinity stress.

This study uses molecular simulations to investigate how cholesterol distributes in lipid bilayers under different temperatures and concentrations, finding strong correlations with phase behavior.

This study identifies heparan sulfate as a critical regulator of G6b-B, showing it inhibits platelet and megakaryocyte function through Shp1/Shp2 signaling.

The paper identifies and analyzes wheat ZIFL transporters, showing their differential expression under Fe and Zn stress and heavy metal exposure.

This study identifies KMT2D as a tumor suppressor in melanoma, showing its loss leads to metabolic reprogramming toward glycolysis and dependence on IGF signaling, suggesting therapeutic targeting of these pathways.

This study compares viral characteristics in two HIV-1C infected monozygotic twins with differing elite neutralizing antibody profiles, identifying viral mutations associated with neutralization resistance and susceptibility.

The paper identifies a negative feedback loop between membrane tension and the CLIC/GEEC pathway mediated by vinculin and GBF1.

The paper develops two in vitro assays to screen inhibitors of ETS transcription factors and finds that lower affinity DNA-binding sequences enhance compound inhibition.

This study identifies and characterizes NF-Y transcription factors involved in rice endosperm development, showing sub-functionalization and interaction patterns among subunits.

The paper shows that the glutathione and thioredoxin systems in P. falciparum can functionally complement each other, compensating for the absence of key antioxidant proteins in certain compartments.