Author

S.-J. Deng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:rat· 2 Assay:structural biology· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. Gu· 3 shared X. Cao· 3 shared X. Wang· 3 shared C. Wu· 2 shared F. Jia· 2 shared H. E. Xu· 2 shared J. Liu· 2 shared K. Wu· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiophysics

C. Gu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.1 and BA.2 variants and their mouse origins

Y. Xu, C. Wu, X. Cao, C. Gu, H. Liu, M. Jiang, X. Wang, Q. Yuan, K. Wu, J. Liu, X. He, D. Wang, X. Wang, S.-J. Deng, H. E. Xu, W. Yin

This study investigates the structural and biochemical features of Omicron BA.1 and BA.2 variants, showing increased infectivity and mouse ACE2 binding compared to wildtype, suggesting a potential human-cat-mouse-human transmission cycle.

bioRxiv · Apr 12, 2022 · PreprintBiophysics

Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody: mechanisms for the high infectivity, immune evasion and antibody drug discovery

W. Yin, Y. Xu, P. Xu, X. Cao, C. Wu, C. Gu, X. He, X. Wang, S. Huang, Q. Yuan, K. Wu, W. Hu, Z. Huang, J. Liu, Z. Wang, , H. E. Xu

bioRxiv · Dec 27, 2021 · PreprintBiophysics

A human antibody with blocking activity to RBD proteins of multiple SARS-CoV-2 variants including B.1.351 showed potent prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus macaques

C. Gu, X. cao, Z. Wang, X. Hu, Y. Yao, Y. Zhou, P. Liu, X. Liu, G. Gao, X. Hu, H. Liang, Z. Chen, L. Gao, Y. Peng, F. Jia, , S.-J. Deng

bioRxiv · Feb 7, 2021 · PreprintMicrobiology