Author
X. S. Xie
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2023 · peak 6/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links13 papers
Recent·Most cited
- ImmunologybioRxiv
Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
Y. Cao, F. Jian, J. Wang…·X. S. Xie
The paper shows that convergent evolution of Omicron variants evades antibodies from BA.5 infections while maintaining ACE2 binding, driven by immune imprinting.
DOI 10.1038/s41586-022-05644-7 - ImmunologybioRxiv
Further humoral immunity evasion of emerging SARS-CoV-2 BA.4 and BA.5 subvariants
F. Jian, Y. Yu, W. Song…·Y. Cao
This study shows that BA.4.6, BA.4.7, and BA.5.9 subvariants with R346 mutations evade humoral immunity more effectively than BA.4/BA.5, reducing neutralization titers by 1.5-2.6-fold.
DOI 10.1016/s1473-3099(22)00642-9 - ImmunologybioRxiv
Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents
Y. R. Cao, F. Jian, Z. Zhang…·X. S. Xie
The paper identifies a potent and broad sarbecovirus-neutralizing antibody cocktail, SA55+SA58, from SARS convalescents to combat Omicron variants and other fast-evolving viruses.
DOI 10.1016/j.celrep.2022.111845 - ImmunologybioRxiv
Characterizations of enhanced infectivity and antibody evasion of Omicron BA.2.75
Y. Cao, W. Song, L. Wang…·X. Wang
This study characterizes the enhanced infectivity and antibody evasion properties of the SARS-CoV-2 Omicron subvariant BA.2.75 compared to BA.5 and other variants.
DOI 10.1016/j.chom.2022.09.018 - ImmunologybioRxiv
BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection
Y. R. Cao, A. Yisimayi, F. Jian…·X. S. Xie
This study investigates antibody evasion by SARS-CoV-2 Omicron sublineages BA.2.12.1, BA.4, and BA.5 against plasma from vaccination and BA.1 infection, showing increased neutralization escape.
DOI 10.1038/s41586-022-04980-y - ImmunologybioRxivPreprint
Omicron BA.2 specifically evades broad sarbecovirus neutralizing antibodies
Y. Cao, A. Yisimayi, F. Jian…·X. S. Xie
This study shows that BA.2 causes stronger antibody evasion than BA.1, particularly in SARS convalescents, and identifies key mutations responsible for this escape.
DOI 10.1101/2022.02.07.479349 - BiophysicsbioRxivPreprint
Structural and functional characterizations of altered infectivity and immune evasion of SARS-CoV-2 Omicron variant
Z. Cui, P. Liu, N. Wang…·X. Wang
The paper characterizes structural and functional changes in the SARS-CoV-2 Omicron variant's Spike protein, identifying new immune escape sites and providing insights for vaccine development.
DOI 10.1101/2021.12.29.474402 - ImmunologybioRxiv
Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies
Y. R. Cao, J. Wang, F. Jian…·X. S. Xie
This study identifies how Omicron evades neutralizing antibodies by analyzing mutations and their effects on different epitope groups, showing over 85% of tested antibodies are escaped.
DOI 10.1038/s41586-021-04385-3 - BioengineeringbioRxiv
Protein and Lipid Mass Concentration Measurement in Tissues by Stimulated Raman Scattering Microscopy
S. Oh, C. Lee, W. Yang…·M. W. Kirschner
The paper introduces NoRI, a SRS microscopy method to measure protein, lipid, and water concentrations in tissues, showing cell-specific variations and disease-related changes in Alzheimer's models.
- BiochemistrybioRxiv
Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants
S. Du, P. Liu, Z. Zhang…·J. Xiao
This study identifies two potent monoclonal antibodies against the B.1.351 variant and shows their efficacy against other variants, suggesting their use as an antibody cocktail.
DOI 10.1038/s41422-021-00555-0 - Cell BiologybioRxiv
CTCF-mediated Chromatin Structures Dictate the Spatio-temporal Propagation of Replication Foci
Q. P. Su, Z. W. Zhao, L. Meng…·Y. Sun
The paper visualizes replication foci during S-phase and reveals a CTCF-dependent hierarchical radial propagation pattern that reverses directionality over time.