L. Qu

Synergically enhanced anti-tumor immunity of in vivo CAR by circRNA vaccine boosting

This study develops circRNA-based in vivo CAR and vaccines that synergistically enhance anti-tumor immunity in mice.

Rapid evolution of fine-scale recombination during domestication: a perspective from population genomics

The paper constructs a fine-scale recombination map in domestic chickens to study rapid evolutionary changes in recombination rates during domestication.

Self-inspired learning to denoise for live-cell super-resolution microscopy

This paper introduces SN2N, a self-supervised denoising method for live-cell super-resolution microscopy that achieves competitive performance without requiring large clean datasets.

Quantitatively mapping local quality of super-resolution microscopy by rolling Fourier ring correlation

This paper introduces a method to quantitatively map the local quality of super-resolution microscopy images, enabling better integration of reconstructions and detection of uncertainties.

Tree and shrub richness modify subtropical tree productivity by modulating the diversity and community composition of soil bacteria and archaea

The paper examines how tree and shrub richness affects tree productivity by altering soil bacterial and archaeal diversity and composition in a subtropical forest experiment.

Non-Invasive Confocal Fluorescence Imaging of Mice Beyond 1700 nm Using Superconducting Nanowire Single-Photon Detectors

This paper develops a non-invasive imaging technique using NIR-IIc light to image deep tissues in mice, achieving imaging depths of ~800 m and visualizing immune structures in lymph nodes.

Circular RNA Vaccines against SARS-CoV-2 and Emerging Variants

This paper develops a circular RNA vaccine encoding SARS-CoV-2 Spike RBD, showing broad protection against multiple variants including Delta and Omicron.

Metapopulation Structure of Diatom-associated Marine Bacteria

The paper investigates the metapopulation structure of marine bacteria associated with diatoms, finding that closely related bacterial populations are host-specific and show functional differentiation.

Endonuclease activity of RecJ from extremely alkaliphilic Bacillus alcalophilus

This study identifies a novel RecJ from Bacillus alcalophilus with endonuclease activity, distinct from previously known exonucleases, and highlights its potential as a gene editing tool.

A common problem in the purification of calicivirus raised by molecular sieving: balance between purification and loss of viral particles

This study evaluates the impact of molecular sieving on Feline Calicivirus stability using cryo-EM and develops a scoring system to assess purification effects.

Optical Sectioning of Live Mammal with Near-Infrared Light Sheet

This paper develops near-infrared light sheet microscopy to image live mammals, revealing tumor dynamics and PD-L1 receptor distribution at the single-cell level.