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This study shows that retinoic acid signaling reduces SEM cell formation and atherosclerosis by epigenetically repressing SEM cell marker genes through RAR/EZH2 complex recruitment and histone modification changes.

This study evaluates how three tank-mix additives affect the biological efficacy and phytotoxicity of copper formulations against two fungal pathogens in apple crops.

This study identifies the podocytic IL-15/STAT5 pathway as a protective mechanism in FSGS, showing that IL-15 alleviates glomerular injury by maintaining autophagy.

This study identifies novel small-molecule inhibitors of SARS-CoV-2 main protease that suppress viral replication in human cells.

The paper discovers a new aphid-transmitted rice virus, RTIV, from wild rice plants and shows it causes low-tillering disease in rice cultivars.

This study shows that deleting CerS6 reduces alcohol-induced fatty liver and improves glucose homeostasis in mice, and links CerS6 expression to ALD progression in humans.

This study develops CNNs to subtype and grade lung adenocarcinoma, achieving high accuracy and outperforming most pathologists in grading prediction.

This study identifies and analyzes lncRNAs in western honey bee larvae infected with Ascosphaera apis, revealing their regulatory roles in immune responses through transcriptome analysis and ceRNA network analysis.

This study analyzes big-data from a tertiary hospital to find that vitamin D deficiency is linked to worse outcomes in COVID-19 patients, including higher hospitalization rates and mortality.

This study identifies PhoP as a key regulator of pathogenicity in Riemerella anatipestifer by combining DAP-seq and transcriptome analysis, showing its role in aerotolerance and virulence.

The paper investigates interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammation, showing increased proximity and functional effects in COPD patients.

The paper identifies delayed gene expression changes in foragers of Melipona quadrifasciata colonies that later collapse, linking them to sublethal factors affecting colony health.

The paper develops a gene-specific machine learning model to improve the prediction of KCNQ2 missense variant pathogenicity with high sensitivity and specificity.

This study shows that suppressing CYP24A1 increases breast cancer cell sensitivity to chemotherapeutic drugs like cisplatin and gefitinib.

The paper investigates the Allee effect in Hymenoscyphus fraxineus, showing that low host density limits inoculum production and disease development.

This paper introduces an improved qPCR method to quantify Fusarium crown rot infection in winter cereals, enabling better breeding for resistance and tolerance.

This study investigates the role of Piezo1 and Piezo2 in osteoarthritis progression by ablating these channels in mice, finding limited effects on joint development and OA severity.

The paper shows surface glia are key in C9orf72-mediated ALS/FTD in Drosophila using genetic tools to mark glial subtypes.

This study evaluates the toxicity and efficacy of TNF-alpha inhibitors adalimumab and infliximab in preventing retinal cell apoptosis and optic nerve axon loss in rabbits after corneal injury.