Author
Worcester Polytechnic Institute
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
A. E. Jones, J. F. Netto, T. L. Foote, Brian N. K. Ruliffson, Catherine F. Whittington
This study investigates how matrix stiffness and obesity-associated signaling influence PANC-1 pancreatic cancer cell behavior in vitro, showing increased invasiveness and amoeboid morphology under combined conditions.
bioRxiv · Jun 11, 2024 · PreprintBioengineering
D. Lu, K. L. Kalantar, V. T. Chu, A. L. Glascock, E. S. Guerrero, N. Bernick, X. Butcher, K. Ewing, E. Fahsbender, O. Holmes, E. Hoops, A. E. Jones, R. Lim, S. McCanny, L. Reynoso, , C. R. Langelier
The paper develops an open-source, cloud-based tool for detecting pathogens and antimicrobial resistance genes in metagenomic and whole-genome sequencing data, demonstrating its application across clinical and environmental studies.
bioRxiv · Apr 12, 2024 · PreprintMicrobiology
A. E. Jones, A. Rios, N. Ibrahimovic, C. Chavez, N. A. Bayley, A. B. Ball, W. Y. Hsieh, A. Sammarco, A. R. Bianchi, A. A. Cortez, T. G. Graeber, A. Hoffmann, S. J. Bensinger, A. S. Divakaruni
This study shows Coenzyme A enhances alternative macrophage activation via MyD88-linked signaling by providing a weak TLR4 signal.
bioRxiv · Mar 28, 2024 · PreprintImmunology
A. Acevedo, A. E. Jones, B. T. Danna, R. Turner, K. P. Montales, C. Beninca, K. Reue, O. S. Shirihai, L. Stiles, M. Wallace, Y. Wang, A. M. Bertholet, A. S. Divakaruni
The paper shows BT2 acts as a mitochondrial uncoupler, reducing ROS and lipogenesis, which may explain its therapeutic benefits in metabolic diseases.
bioRxiv · Aug 15, 2023 · PreprintBiochemistry
Y. Hu, H.-X. Sun, M. Sakurai, A. E. Jones, L. Liu, T. Cheng, C. Zheng, J. Li, B. Ravaux, Z. Luo, Y. Ding, T. Liu, Y. Wu, E. Chen, Z. Chen, , J. Wu
This study identifies RNA sensing and innate immunity in host embryos as a barrier to interspecies chimerism and shows that modifying host embryos can enhance human cell survival in chimeric embryos.
bioRxiv · Mar 7, 2023 · PreprintCell Biology
T. Yan, A. R. Julio, M. Villanueva, A. E. Jones, A. B. Ball, L. M. Boatner, A. C. Turmon, S. L. Yen, H. S. Desai, A. S. Divakaruni, K. M. Backus
The paper develops Cys-LoC and Cys-LOx methods to map compartment-specific cysteine oxidation states, revealing novel mitochondrial redox modifications in response to inflammation.
bioRxiv · Jan 22, 2023Biochemistry
B. R. Desousa, K. K. O. Kim, A. E. Jones, A. B. Ball, W. Y. Hsieh, P. Swain, D. H. Morrow, D. A. Ferrick, A. J. Brownstein, O. S. Shirihai, A. Neilson, D. A. Nathanson, G. W. Rogers, B. P. Dranka, A. N. Murphy, , A. S. Divakaruni
The paper develops a method to calculate ATP production rates from oxidative phosphorylation and glycolysis using Seahorse XF Analyzer data, enabling direct comparison of ATP sources in live cells.
bioRxiv · Apr 16, 2022Biochemistry
M. Veliova, C. Mendes Ferreira, I. Y. Benador, A. E. Jones, B. R. Desousa, K. Mahdaviani, R. Acin-Perez, A. Petcherski, A. S. Divakaruni, M. Prentki, B. E. Corkey, M. Liesa, M. F. Oliveira, O. S. Shirihai
The paper shows that blocking mitochondrial pyruvate import increases ATP synthesis via futile lipid cycling in brown adipocytes, enhancing energy expenditure without adrenergic stimulation.
bioRxiv · Nov 15, 2019 · PreprintBiochemistry
E. A. Assali, A. E. Jones, M. Veliova, M. Taha, N. Miller, M. Shum, M. F. Oliveira, G. Las, M. Liesa, I. Sekler, O. S. Shirihai
This study identifies NCLX as a critical mitochondrial Na+/Ca2+ exchanger that prevents cell death during adrenergic activation of brown adipose tissue by mitigating Ca2+ overload.
bioRxiv · Nov 6, 2018Physiology