C. J. Staiger

A Ralstonia solanacearum type III effector alters the actin and microtubule cytoskeleton to promote bacterial virulence in plants

This study shows that the Ralstonia solanacearum type III effector RipUK60 disrupts plant cytoskeleton organization to enhance bacterial virulence.

Yeast and Mammalian Epsins Use Different Determinants for Localization and Function: Role of Clathrin/AP2/Ubiquitin Binding Motifs and Poly-Glutamine Stretches

This study compares yeast and mammalian Epsin localization and function, identifying differences in binding determinants and highlighting the role of poly-glutamine stretches.

Cooperative actin filament nucleation by the Arp2/3 complex and formins maintains the homeostatic cortical array in Arabidopsis epidermal cells

The paper investigates how Arp2/3 complex and formins cooperate to maintain the cortical actin array in Arabidopsis epidermal cells through single filament dynamics and genetic inhibition.

Point mutations in the catalytic domain disrupt cellulose synthase (CESA6) vesicle trafficking and protein dynamics

A comprehensive mutational analysis of the catalytic domain of Arabidopsis CESA6 reveals distinct roles for conserved motifs in CSC vesicle trafficking, protein complex formation, or protein dynamics.

RORA regulates neutrophil migration and activation in zebrafish

This study identifies miR-99 and ROR as regulators of neutrophil migration and anti-microbial defense in zebrafish.

Revising the Role of Cortical Cytoskeleton During Secretion: Actin and Myosin XI Function in Vesicle Tethering

The paper quantifies vesicle tethering during plant secretion and shows actin and myosin XI are required for this process, while microtubules have a minor effect.

Arabidopsis Myosin XIK Interacts with the Exocyst Complex to Facilitate Vesicle Tethering during Exocytosis

This study shows Arabidopsis myosin XIK interacts with the exocyst complex to facilitate vesicle tethering during exocytosis, revealing a role in secretory processes in plants.

MOLECULAR DETERMINANTS OF THE ENDOCYTIC PROTEIN EPSIN CONTROLLING ITS LOCALIZATION AND FUNCTION IN CANCER CELL MIGRATION AND INVASION

This study identifies the C-terminal motifs of epsin proteins as critical for their localization and function in cancer cell migration and invasion, with clathrin-binding motifs being most important.

Pollen tube-triggered accumulation of NORTIA at the filiform apparatus facilitates fertilization in Arabidopsis thaliana

The paper shows that NORTIA accumulation at the filiform apparatus is essential for pollen tube reception in Arabidopsis thaliana.

Endosidin20 targets cellulose synthase catalytic domain to inhibit cellulose biosynthesis

Endosidin20 inhibits cellulose synthesis by targeting the catalytic site of CESA6, reducing cellulose synthase complex delivery to the plasma membrane.

Auxin-Induced Actin Cytoskeleton Rearrangements Require AUX1

This study quantifies actin cytoskeleton responses to short-term auxin treatment and shows AUX1 is necessary for actin remodeling in Arabidopsis root cells.

Arabidopsis Myosins XI Are Involved in Exocytosis of Cellulose Synthase Complexes

This study shows that myosin XI and the actin cytoskeleton are essential for delivering cellulose synthase complexes to the plasma membrane in Arabidopsis, affecting cellulose biosynthesis.