Author

D. Meng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Cell Biology· 1 Ecology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Research Focus:chromatin & epigenetic regulation· 3 Organism:Arabidopsis· 2 Research Focus:differential expression· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

M. Nordborg· 2 shared T. Tsuchimatsu· 2 shared A. G. Jegga· 1 shared A. Hedhly· 1 shared A. Platzer· 1 shared A.-C. Holl· 1 shared C. Gao· 1 shared C. Liu· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersEvolutionary Biology

M. Nordborg

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Author profile →

6 papers

Recent·Most cited

Super Pangenome of Grapevines Empowers Improvement of the Oldest Domesticated Fruit

L. Guo, X. Wang, D. H. Ayhan, M. S. Rhaman, M. Yan, J. Jiang, D. Wang, W. Zheng, J. Mei, W. Ji, J. Jiao, S. Chen, J. Sun, S. Yi, D. Meng, , W. Ye

The paper assembles and annotates haplotype-resolved genomes of grapevines to uncover genetic diversity and disease resistance mechanisms, identifying structural variants linked to downy mildew resistance.

bioRxiv · Feb 28, 2024 · PreprintPlant Biology

Perturbations of glutathione and sphingosine metabolites in Port Wine Birthmark patient-derived induced pluripotent stem cells

V. Nguyen, J. Kravitz, C. Gao, M. L. Hochman, D. Meng, D. Chen, Y. Wang, A. G. Jegga, S. Nelson, W. Tan

This study identifies metabolic perturbations in PWB-derived iPSCs, showing upregulated glutathione and downregulated sphingolipid metabolism, which may contribute to laser resistance in PWB vasculature.

bioRxiv · Jul 18, 2023 · PreprintCell Biology

HSP90 inhibitor NVP-HSP990 alleviates rotavirus infection

Y. Cao, Q. Zhu, X. Wu, Z. Xie, C. Yang, Y. Guo, D. Meng, X. Zhou, Y. Wu, J. Li, h. He

This study shows that NVP-HSP990, a HSP90 inhibitor, effectively reduces rotavirus infection in vitro and in mice by inhibiting replication and alleviating intestinal damage.

bioRxiv · Jun 15, 2023 · PreprintMicrobiology

Local and global chemical shaping of bacterial communities by redox potential

J. M. Dick, D. Meng

The paper examines correlations between redox potential and carbon oxidation state in microbial communities across seven environments, finding positive global correlations in bacterial communities but not archaeal ones.

bioRxiv · Oct 12, 2021Ecology

Adaptive Reduction of Male Gamete Number in a Selfing Species

T. Tsuchimatsu, H. Kakui, M. Yamazaki, C. Marona, H. Tsutsui, A. Hedhly, D. Meng, Y. Sato, T. Stadler, U. Grossniklaus, M. M. Kanaoka, M. Lenhard, M. Nordborg, K. K. Shimizu

The paper uses GWAS to show polygenic selection on pollen number in Arabidopsis thaliana, identifies a gene affecting pollen number, and validates its causal role using CRISPR-Cas9 mutants.

bioRxiv · Feb 28, 2018Evolutionary Biology

Patterns of polymorphism at the self-incompatibility locus in 1,083 Arabidopsis thaliana genomes

T. Tsuchimatsu, P. Goubet, S. Gallina, A.-C. Holl, I. Fobis-Loisy, H. Berges, W. Marande, E. Prat, D. Meng, Q. Long, A. Platzer, M. Nordborg, X. Vekemans, V. Castric

The paper analyzes polymorphism at the S-locus in 1,083 Arabidopsis thaliana genomes to understand the historical loss of self-incompatibility, finding multiple independent origins and recombination events during post-glacial colonization.

bioRxiv · Jan 4, 2017Evolutionary Biology