Obesity modifies cell fate plasticity of Pdgfrα-expressing adipocyte progenitors to promote an aberrant mammary microenvironment
S. A. Kwende, P. Nuthalapati, J. P. Sunder Singh, S. Maity, D. Ning, D. G. Shryock, Z. Xuan, P. A. Joshi
This study identifies obesity-induced changes in PDGFRα-expressing adipocyte progenitors that promote a cancer-susceptible mammary microenvironment through EGFR-mediated pathways.
bioRxiv · Dec 28, 2023 · PreprintCell Biology