The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney
P. Katti, P. Prasad, S. K. Masenga, P. Venkhatesh, Z. Vue, A. G. Marshall, B. Rodrageaz, H. Le, E. Garza-Lopez, A. Murphy, B. Jenkins, A. Kadam, J. Shao, A. Crabtree, P. Martin, , McReyn
This study investigates age-related mitochondrial structural deficits in the kidney, finding that the MICOS complex is impaired, leading to increased oxidative stress and mitochondrial dysfunction.
bioRxiv · Jun 9, 2024Physiology