The seven transmembrane domain protein MoRgs7 functions in surface perception and undergoes coronin MoCrn1-dependent endocytosis in complex with Gα subunit MoMagA to promote cAMP signaling and appressorium formation in Magnaporthe oryzae
X. Li, K. Zhong, Z. Yin…·Kaili Zhong, Ziyi Yin, Jiexiong Hu, Lianwei Li, Haifeng Zhang, Xiaobo Zheng, Ping Wang, Z, Xiao Li
The paper identifies MoRgs7 as a GPCR-like receptor in Magnaporthe oryzae that senses hydrophobic surfaces via hydrophobic interactions, couples with Gα subunit MoMagA for endocytosis, and promotes cAMP signaling required for appressorium formation and pathogenicity.