L. Shen

The paper investigates how SARS-CoV-2 infection induces epithelial-mesenchymal transition (EMT) in lung cancer models, leading to changes in gene expression and potential therapeutic targets.

This study shows that blocking CTLA-4 reverses Treg cell suppression of anti-TB T-cell responses in tuberculosis patients.

This study identifies Ppd-1's role in regulating floral development and spike architecture in wheat, linking it to grain yield through phenotypic and transcriptomic analyses.

The paper identifies CREBBP/EP300 as radiosensitization targets in mutant tumors by inhibiting histone acetyltransferase, which represses homologous recombination and increases radiation sensitivity.

The paper shows that inhibiting nonsense-mediated decay increases expression of p53β/γ isoforms, which are resistant to MDM2 degradation, thereby restoring p53 function in cancers with MDM2 amplification, HPV infection, or specific p53 mutations.

This study shows that KLF14 overexpression reduces infarct size and preserves cardiac function after myocardial infarction by protecting mitochondria and increasing PGC-1 levels.

The paper improves the Coriolis μ air sampler by introducing operational and technical modifications to enhance sample recovery and biosafety during microbiological air sampling.

Track-Control provides an automated real-time closed-loop system for behavioral assays, enabling efficient and flexible control of experimental conditions.

The study evaluates bacterial contamination of computer equipment in a hospital, finding mouse pads are highly contaminated and require daily cleaning.

This study determines the structure of an E. coli transcription activation complex and shows that Crl stabilizes σS to activate transcription without DNA contact.

This study identifies and genotypes Trichosporon species isolated from giant pandas, finding 11 species with varying pathogenicity and genotypes.