M. Torres

Elasmobranchs Exhibit Species-Specific Epidermal Microbiomes Guided by Denticle Topography

This study shows that elasmobranch sharks have species-specific epidermal microbiomes influenced by denticle morphology and phylogeny.

Impact of inoculation practices on microbiota assembly and community stability in a fabricated ecosystem

This study evaluates how different inoculation practices and harvesting times affect microbial community reproducibility in a fabricated ecosystem with Brachypodium distachyon.

SEL1L-HRD1 interaction is prerequisite for the formation of a functional HRD1 ERAD complex

This study shows that the SEL1L-HRD1 interaction is essential for HRD1 ERAD complex function, as its disruption leads to developmental defects and cerebellar ataxia in mice.

Identification of Circular Dorsal Ruffles as Signal Platforms for the AKT pathways in Glomerular Podocytes

The paper identifies circular dorsal ruffles as signal platforms for the AKT-mTORC1 pathway in glomerular podocytes, linking them to kidney function and potential therapeutic targets.

Unlike Chloroquine, mefloquine inhibits SARS-CoV-2 infection in physiologically relevant cells and does not induce viral variants.

This paper shows mefloquine inhibits SARS-CoV-2 infection in relevant cells more effectively than chloroquine without promoting viral mutations.

Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes

This study shows that a proinsulin mutation increases susceptibility to diet-induced diabetes in mice, with severity linked to genetic dosage and beta-cell dysfunction.

The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy of the antibody

The paper identifies SC31, a potent SARS-CoV-2 neutralizing antibody, and shows that its Fc-mediated effector functions are critical for its therapeutic efficacy in vivo.

Structural basis of αE-catenin-F-actin catch bond behavior

The paper describes the cryo-EM structure of E-catenin's actin-binding domain and explains how mechanical force affects its binding to F-actin, revealing the mechanism of catch bond behavior.

Cancer LncRNA Census 2 (CLC2): an enhanced resource reveals clinical features of cancer lncRNAs

CLC2 expands the catalog of cancer lncRNAs to 492, including 95 novel ones, and links them to clinical and genomic features for precision medicine.

Repeated colonization of caves leads to phenotypic convergence in catfishes (Siluriformes: Trichomycterus) at a small geographical scale

This study shows that cave-dwelling catfishes in the genus Trichomycterus in Colombia have been independently colonized by two separate clades, leading to phenotypic convergence despite different colonization events.