Author

S. Sidhu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Ecology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Bell· 1 shared A. Choi· 1 shared A. F. Alpi· 1 shared A. Gross· 1 shared A. S. Kim· 1 shared B. Freedman· 1 shared B. Liu· 1 shared B. Schulman· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperPathology

A. Bell

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

CD8 T-cell dysfunction is linked with CAR T-cell failure and can be mitigated by a non-alpha IL-2 agonist, pegenzileukin

P. K. Reville, I. N. Sheikh, A. Choi, E. Dai, J. Henderson, X. Li, E. Rojas, C. C. Le, C. Okwuchi, M. Devonish, R. Carrio, N. Pate, K. Malley, D. Bangari, J.-A. Givigan, , M. R. Green

The paper identifies dysfunctional CD8 CAR T-cells in rrLBCL tumors and shows that pegenzileukin mitigates this dysfunction, improving CAR T-cell responses.

bioRxiv · Aug 28, 2023 · PreprintImmunology

Dynamic control of metabolic zonation and liver repair by endothelial cell Wnt2 and Wnt9b revealed by single cell spatial transcriptomics using Molecular Cartography

S. Hu, S. Liu, B. Yu, M. Poddar, S. Singh, C. Cao, J. McGaughey, A. Bell, L. L. Blazer, J. Adams, S. Sidhu, S. Angers, S. P. Monga

This study identifies endothelial cell Wnt2 and Wnt9b as key regulators of liver zonation and repair, showing their therapeutic potential in acute liver failure using single-cell spatial transcriptomics.

bioRxiv · Mar 18, 2022Pathology

Differential UBE2H-CTLH E2-E3 ubiquitylation modules regulate erythroid maturation

D. Sherpa, J. Mueller, O. Karayel, J. Chrustowicz, P. Xu, K. V. Gottemukkala, C. Baumann, A. Gross, O. Czarnezki, W. Zhang, J. Gu, J. Nilvebrant, M. J. Weiss, S. Sidhu, P. J. Murray, , A. F. Alpi

The paper identifies UBE2H-CTLH ubiquitylation modules that regulate stages of human erythropoiesis, showing their role in controlling maturation and heme synthesis.

bioRxiv · Jan 18, 2022 · PreprintCell Biology

Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress

J. Liang, G. Ruthel, C. Sagum, M. T. Bedford, S. Sidhu, M. Sudol, C. K. Jaladanki, H. Fan, B. Freedman, R. N. Harty

This study identifies WWOX as a host protein that interacts with viral PPxY motifs to inhibit virus egress, revealing a competitive interplay with angiomotin.

bioRxiv · Jan 26, 2021Microbiology

Using Citizen Science to build baseline data on tropical tree phenology

G. Ramaswami, S. Sidhu, S. Quader

This study uses a citizen science initiative to collect phenological data on tropical tree species in India, revealing seasonal patterns and potential shifts in phenology, particularly for Cassia fistula.

bioRxiv · Aug 28, 2020Ecology

Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2.

J. B. Case, P. W. Rothlauf, R. E. Chen, Z. Liu, H. Zhao, A. S. Kim, L.-M. Bloyet, Q. Zeng, S. Tahan, L. Droit, M. X. G. Ilagan, M. A. Tartell, G. K. Amarasinghe, J. P. Henderson, S. Miersch, , S. P. J. Whelan

This study develops two neutralization assays for SARS-CoV-2 using VSV and a clinical isolate, showing high concordance between monoclonal, polyclonal antibodies, and ACE2-Fc in neutralizing activity.

bioRxiv · May 18, 2020Microbiology