Author

S.-Y. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 2 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. J. Davis· 2 shared C. Zhang· 2 shared H. Chen· 2 shared J. Saha· 2 shared X. Wang· 2 shared A. Facoetti· 1 shared A. Pompos· 1 shared A. Zumla· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. J. Davis

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Defective Homologous Recombination and Genomic Instability Predict Increased Responsiveness to Carbon Ion Radiotherapy in Pancreatic Cancer

B. J. Sishc, J. Saha, E. Polsdofer, L. Ding, H. Lu, S.-Y. Wang, K. L. Swancutt, J. H. Nicholson, A. Facoetti, A. Pompos, M. Ciocca, T. A. Aguilera, M. D. Story, A. J. Davis

This study identifies PDAC cell lines defective in homologous recombination or with high genomic instability as more responsive to carbon ion radiotherapy, suggesting potential for targeted therapy.

bioRxiv · Apr 8, 2024Cancer Biology

Cancer cell-autonomous cGAS-STING response confers drug resistance

Q.-M. Lv, S.-Y. Wang, H.-M. Lei, K.-R. Zhang, Y.-B. Tang, Y. Shen, L.-M. Lu, H.-Z. Chen, L. Zhu

This study shows that cGAS-STING signaling in cancer cells promotes drug resistance by responding to cytosolic DNA from chemotherapy, suggesting caution in combining STING agonists with chemotherapy.

bioRxiv · Oct 23, 2021Cancer Biology

Ablating Ku70 phosphorylation results in defective DNA damage repair and spontaneous induction of hepatocellular carcinoma

J. Saha, J. Bae, S.-y. Wang, L. J. Chappell, P. Gopal, A. J. Davis

This study shows that ablation of Ku70 phosphorylation leads to defective DNA repair and spontaneous hepatocellular carcinoma in mice.

bioRxiv · Mar 3, 2021Cancer Biology

Single-cell landscape of immunological responses in COVID-19 patients

F.-S. Wang, J.-Y. Zhang, X. Wang, X. Xing, Z. Xu, C. Zhang, J.-W. Song, X. Fan, P. Xia, J.-L. Fu, S.-Y. Wang, R.-N. Xu, X.-P. Dai, L. Shi, L. Huang, , F. Bai

This study analyzes immune responses in COVID-19 patients using single-cell RNA sequencing to identify differences in immune cell behavior across disease severity stages.

bioRxiv · Jul 23, 2020Immunology

TCR repertoire analysis reveals effector memory T cells differentiation into Th17 cells in rheumatoid arthritis

X. Jiang, S.-y. Wang, C. Zhou, J.-h. Wu, Y.-h. Jiao, L.-y. Lin, X. Lu, B. Yang, W. Zhang, X.-y. Xiao, Y.-t. Li, X.-y. Wu, X. Wang, H. Chen, L.-d. Zhao, , X. Zhang

This study analyzes TCR repertoires in RA patients and identifies clonal expansion and shared repertoires between EMT and Th17 cells, correlating TCR diversity with disease activity.

bioRxiv · Apr 23, 2019 · PreprintImmunology

AhRLK1, a CLAVATA1-like leucine-rich repeat receptor-like kinase of peanut, confers increased resistance to bacterial wilt in tobacco

C. Zhang, H. Chen, R.-R. Zhuang, Y.-T. Chen, Y. Deng, T.-C. Cai, S.-Y. Wang, Q.-Z. Liu, R.-H. Tang, S. Shan, R.-L. Pan, L.-S. Chen, W.-J. Zhuang

This study identifies AhRLK1, a peanut receptor-like kinase, which enhances resistance to Ralstonia solanacearum in tobacco through hypersensitive response and hormone signaling.

bioRxiv · Sep 28, 2018Plant Biology