Super-immunity by broadly protective nanobodies to sarbecoviruses
Y. Xiang, W. Huang, H. Liu, Z. Sang, S. Nambulli, J. Tubiana, K. L. Williams, P. Duprex, D. Schneidman-Duhovny, I. A. Wilson, D. J. Taylor, Y. Shi
The paper isolates and characterizes ultrahigh-affinity nanobodies from a camelid immunized with SARS-CoV-2 RBD, showing broad sarbecovirus neutralization and structural insights.
bioRxiv · Dec 26, 2021 · PreprintMicrobiology